Yu YF, Cao YD. Effect of intraoperative cell rescue on bleeding related indexes after cesarean section. World J Clin Cases 2022; 10(8): 2439-2446 [PMID: 35434071 DOI: 10.12998/wjcc.v10.i8.2439]
Corresponding Author of This Article
Yu-Fang Yu, MBChB, Technician, Department of Blood Transfusion, Hai’an People’s Hospital Affiliated to Nantong University, No. 17 Zhongba Middle Road, Hai’an 226600, Jiangsu Province, China. yyfang125@163.com
Research Domain of This Article
Obstetrics & Gynecology
Article-Type of This Article
Observational Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Mar 16, 2022; 10(8): 2439-2446 Published online Mar 16, 2022. doi: 10.12998/wjcc.v10.i8.2439
Effect of intraoperative cell rescue on bleeding related indexes after cesarean section
Yu-Fang Yu, Yong-Dong Cao
Yu-Fang Yu, Department of Blood Transfusion, Hai’an People’s Hospital Affiliated to Nantong University, Hai’an 226600, Jiangsu Province, China
Yong-Dong Cao, Department of Clinical Laboratory, Hai’an Qutang Central Health Center, Hai’an 226600, Jiangsu Province, China
Author contributions: Yu YF wrote the manuscript; Cao YD participated in data analysis.
Institutional review board statement: The study was approved by the Ethics Committee of Hai’an People’s Hospital Affiliated to Nantong University.
Informed consent statement: All patients gave informed consent.
Conflict-of-interest statement: No benefits in any form have been received or will be received from a commercial party related directly or indirectly to the subject of this article.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at yyfang125@163.com.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yu-Fang Yu, MBChB, Technician, Department of Blood Transfusion, Hai’an People’s Hospital Affiliated to Nantong University, No. 17 Zhongba Middle Road, Hai’an 226600, Jiangsu Province, China. yyfang125@163.com
Received: December 1, 2021 Peer-review started: December 1, 2021 First decision: December 27, 2021 Revised: January 12, 2022 Accepted: January 27, 2022 Article in press: January 27, 2022 Published online: March 16, 2022
ARTICLE HIGHLIGHTS
Research background
Obstetric hemorrhage is the leading cause of maternal mortality globally, especially in China. The key to a successful rescue is immediate and rapid blood transfusion. Autotransfusion has become an integral part of clinical blood transfusion, with intraoperative cell salvage (IOCS) being the most widely used.
Research motivation
In this paper, the application of IOCS in cesarean section, monitoring of amniotic fluid embolization, and other related indications are discussed, demonstrating its safety in cesarean section.
Research objectives
This study aimed to investigate the application of IOCS in cesarean section.
Research methods
A total of 87 patients who underwent cesarean section and blood transfusion in our hospital from March 2015 to June 2020 were enrolled in this prospective controlled study.
Research results
Before and after transfusion, no significant differences were observed in hemor-heology and the coagulation function indices between the two groups. About 24 h after transfusion, the erythrocyte count, platelet ratio, and fibrinogen value significantly decreased in the two groups; the PLT value significantly decreased in the two groups; the activated partial thromboplastin time, prothrombin time, and activated clotting time significantly increased in the two groups; and no statistical differences were observed in the hemorheology and coagulation function indices between the two groups. Furthermore, there was no significant difference in the incidence of adverse reactions between the two groups.
Research conclusions
IOCS has a negligible effect on hemorheology and coagulation function in patients undergoing cesarean section and does not increase the risk of amniotic fluid embolism.
Research perspectives
The principle of IOCS should be strictly followed during operation, which is worth promoting.
