Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Feb 26, 2021; 9(6): 1483-1489
Published online Feb 26, 2021. doi: 10.12998/wjcc.v9.i6.1483
Polidocanol sclerotherapy for multiple gastrointestinal hemangiomas: A case report
Huan Yao, Yu-Xin Xie, Jian-Yi Guo, Hui-Chao Wu, Rui Xie, Guo-Qing Shi
Huan Yao, Yu-Xin Xie, Jian-Yi Guo, Hui-Chao Wu, Rui Xie, Guo-Qing Shi, Department of Gastroenterology, Affiliated Hospital of Zunyi Medical University, Zunyi 563003, Guizhou Province, China
Author contributions: Yao H and Xie YX contributed equally to this article; Yao H wrote the paper; Guo JY collected the case data; Shi GQ performed the endoscopic examination and treatment; Wu HC performed endoscopic ultrasound; Xie R revised the paper.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to report.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Guo-Qing Shi, Doctor, Professor, Department of Gastroenterology, Affiliated Hospital of Zunyi Medical University, No. 149 Dalian Road, Zunyi 563003, Guizhou Province, China.
Received: November 14, 2020
Peer-review started: November 14, 2020
First decision: December 3, 2020
Revised: December 16, 2020
Accepted: December 27, 2020
Article in press: December 27, 2020
Published online: February 26, 2021

Gastrointestinal (GI) hemangioma has a low incidence among systemic hemangiomas, and some GI hemangiomas occur in the intestine, stomach, and esophagus. Polidocanol has been increasingly used in sclerotherapy. However, this paper reports that minimally invasive treatment of multiple hemangiomas with large diameters can achieve satisfactory results by multipoint injection.


A 46-year-old female patient was hospitalized in another hospital for cough. We accidentally found thickening of the lower esophagus by chest computed tomography. The patient was eventually diagnosed with multiple GI hemangiomas and underwent a series of examinations including esophagogastroduodenoscopy (EGD), endoscopic ultrasound, and magnetic resonance imaging. We calculated the dose of polidocanol according to the volumes of the hemangiomas, fixed the target vein with the help of a transparent cap, and then administered polidocanol via multipoint injection into the hemangiomas under endoscopic guidance. EGD and endoscopic ultrasound showed that the hemangiomas disappeared. The color of the esophageal mucosa returned to normal 1 mo after sclerotherapy.


Sclerotherapy may be a safe and effective method for treating multiple hemangiomas of the alimentary canal.

Keywords: Hemangioma, Polidocanol, Sclerotherapy, Stomach, Esophagus, Case report

Core Tip: Multiple gastrointestinal (GI) hemangiomas are rare in clinical practice, and the current treatment method for lager GI hemangiomas is surgery. In this case, multipoint injection of polidocanol was used to treat gastroesophageal hemangiomas. We used a reasonable dose of polidocanol and applied the treatment using a transparent cap. This sclerotherapy method successfully treated a patient with multiple hemangiomas without any complications.