Bai B, Mao CS, Li Z, Kuang SL. Endoscopic ultrasonography diagnosis of gastric glomus tumors. World J Clin Cases 2021; 9(33): 10126-10133 [PMID: 34904082 DOI: 10.12998/wjcc.v9.i33.10126]
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Nov 26, 2021; 9(33): 10126-10133 Published online Nov 26, 2021. doi: 10.12998/wjcc.v9.i33.10126
Endoscopic ultrasonography diagnosis of gastric glomus tumors
Bing Bai, Chong-Shan Mao, Zhen Li, Sheng-Li Kuang
Bing Bai, Zhen Li, Oncology Center, Henan Provincial People's Hospital (People's Hospital of Zhengzhou University), Zhengzhou 450003, Henan Province, China
Chong-Shan Mao, Public Health Medical Center, Henan Provincial People's Hospital (People's Hospital of Zhengzhou University), Zhengzhou 450003, Henan Province, China
Sheng-Li Kuang, Department of Digestive Disease, Henan Provincial People's Hospital, Zhengzhou 450003, Henan Province, China
Author contributions: Bai B, Mao CS, Li Z and Kuang SL contributed equally to this work; Bai B designed the research study; Mao CS performed the case search; Li Z analyzed the data; Kuang SL wrote the manuscript; all authors have read and approved the final manuscript.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of the Henan Provincial People's Hospital.
Informed consent statement: The study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: We declare that we do not have any commercial or associative interest that represents a conflict of interest in connection with the work submitted.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Received: May 28, 2021 Peer-review started: May 28, 2021 First decision: July 1, 2021 Revised: July 3, 2021 Accepted: October 11, 2021 Article in press: October 11, 2021 Published online: November 26, 2021
Abstract
BACKGROUND
A gastric glomus tumor is relatively rare, and there is little knowledge on its endoscopic ultrasound findings.
AIM
To assess the accuracy of endoscopic ultrasonography (EUS) in the diagnosis of gastric glomus tumor and to discuss its value by reviewing the literature.
METHODS
A retrospective analysis of the EUS characteristics of gastric glomus tumor (such as tumor location, shape, size, echogenicity, homogeneity, margins, layer of origin, and so on) was performed. The study included 12 cases of gastric glomus tumor confirmed by surgery and pathology (7 females and 5 males, age range 36-74 years, average age was 58.2 years).
RESULTS
All the lesions were located in the gastric antrum (12 cases), protruding into the cavity, with a diameter between 1 and 3.5 cm. Glomus tumor of the stomach manifested as a circumscribed and slightly hypoechoic mass in the fourth layer, with an internal heterogeneous echo mixed with hyperechogenic spots and a marginal more hypoechoic halo. Smooth muscle actin, h-caldesmon and vimentin were shown to be positive by immunohistochemistry.
CONCLUSION
Although glomus tumor of the stomach is relatively rare, a typical glomus tumor of the stomach has characteristic changes under EUS.
Core Tip: Gastric glomus tumor is a rare non-epithelial benign vascular tumor and is difficult to diagnose with upper gastrointestinal endoscopy. We summarized the characteristics of endoscopic ultrasonography (EUS), computed tomography (CT) and pathology of 12 cases of gastric glomus tumor confirmed by pathology. The EUS characteristics of a gastric glomus tumor include a hypoechoic lesion originating from the fourth layer with a peripheral acoustic halo. Clinically, the diagnosis can be confirmed by the EUS characteristics combined with CT imaging findings.
