Published online Jan 26, 2021. doi: 10.12998/wjcc.v9.i3.685
Peer-review started: September 12, 2020
First decision: November 30, 2020
Revised: December 4, 2020
Accepted: December 16, 2020
Article in press: December 16, 2020
Published online: January 26, 2021
Herpes simplex virus (HSV) is a highly infectious pathogen that is easily transmitted via the bodily fluids of an infected individual. This virus usually affects individuals older than six months of age, and rarely causes lesions or symptoms in younger patients.
We present the case of a five-month-old healthy girl who presented with painful herpetic gingivostomatitis and perioral vesicles. We discuss the pathophysiology of primary HSV infection and the effect of maternal antibodies on the infant’s immune system. In addition, we explain the diagnosis, management, and prognosis of HSV infection in young infants.
This case highlights the importance of early diagnosis and management of HSV infections to decrease the risk of developing severe complications and death.
Core Tip: Although the herpes simplex virus (HSV) infection is highly contagious, it rarely develops in infants younger than six months of age. Our patient presented with oral and perioral manifestations of HSV type 1 infection. Early diagnosis and management of HSV infections is important to decrease the risk of developing severe complications.