Published online Jan 16, 2021. doi: 10.12998/wjcc.v9.i2.457
Peer-review started: August 25, 2020
First decision: October 27, 2020
Revised: October 28, 2020
Accepted: November 13, 2020
Article in press: November 13, 2020
Published online: January 16, 2021
Paratesticular liposarcoma accounts for approximately 7% of scrotal tumors. They are rare lesions of the reproductive system with approximately 90% of the lesions originating from the spermatic cord. Surgery, with the goal of complete resection, is the mainstay for treatment of this disease. However, treatment consisting of extended resection to decrease local recurrence remains controversial.
We report the cases of two patients with paratesticular liposarcomas who were treated with radical testicular tumor resection without adjuvant therapy. Follow-up investigations at 9 mo showed no sign of recurrence.
Surgery is the first-line treatment, regardless of whether it is a recurrent or primary tumor. Extended resection carries a higher risk of complications and should not be performed routinely. Preoperative radiotherapy can reduce the local recurrence rate without affecting the overall survival.
Core Tip: Atypical liposarcoma/well-differentiated liposarcoma is commonly distributed in the retroperitoneum, deep tissue of the extremities, and mediastinum, but rarely in the scrotum. We report the cases of two patients with paratesticular liposarcomas who were treated with radical testicular tumor resection without adjuvant therapy. The cases highlight surgery as the first choice of treatment, regardless of primary or recurrent liposarcoma, and show that extended resection is not beneficial for overall survival. Further, radiotherapy can provide a balance between the local recurrence rate and overall survival.