Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 16, 2021; 9(2): 422-428
Published online Jan 16, 2021. doi: 10.12998/wjcc.v9.i2.422
Intravitreal dexamethasone implant — a new treatment for idiopathic posterior scleritis: A case report
Yong-Ji Zhao, Yu-Ling Zou, Ying Lu, Meng-Jun Tu, Zhi-Peng You
Yong-Ji Zhao, Yu-Ling Zou, Ying Lu, Zhi-Peng You, Department of Opthalmology, The Second Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China
Meng-Jun Tu, Department of Ophthalmology, The Eye Hospital, Wenzhou Medical University, Wenzhou 330006, Zhejiang Province, China
Author contributions: Zou YL, Lu Y, and Tu MJ treated the patient; Zhao YJ and You ZP drafted the paper; all authors read and approved the final version to be published.
Supported by National Natural Science Foundation of China, No. 81460088 and No. 81860177.
Informed consent statement: The patient provided informed written for the publication of this case report.
Conflict-of-interest statement: The authors declare that there is no conflict of interest in this study.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Zhi-Peng You, PhD, Doctor, Department of Opthalmology, The Second Affiliated Hospital of Nanchang University, No. 1 Minde Street, Nanchang 330006, Jiangxi Province, China.
Received: August 4, 2020
Peer-review started: August 4, 2020
First decision: November 14, 2020
Revised: November 18, 2020
Accepted: November 29, 2020
Article in press: November 29, 2020
Published online: January 16, 2021

Posterior scleritis is one of the most easily missed and misdiagnosed diseases in ophthalmology. In this case we treated a patient with intravitreal dexamethasone implant that has not been extensively studied before.


A 40-year-old female patient who had anxiety, palpitation, and insomnia presented with eye pain and decreased vision in the left eye. An eye examination indicated that her visual acuity (VA) was 40/100. Her left eye presented conjunctival edema, mild exophthalmos, clear cornea, KP(-), and clear aqueous humor. In the fundus, there was a cinerous retinal protuberance. Ultrasonography showed “T-sign” and no systemic association was detected in laboratory examination. One month after injection of dexamethasone implant, the patient exhibited VA of 20/20, fundus serous retinal detachment disappeared, and intraocular pressure of both eyes was at the normal level.


Intravitreal injection of dexamethasone implant may be a safe and effective treatment for patients with idiopathic posterior scleritis.

Keywords: Intravitreal dexamethasone implant, Posterior scleritis, Treatment, Case report, Ophthalmology

Core Tip: We describe a case of using intravitreal dexamethasone implant to treat a patient with idiopathic posterior scleritis.