Case Report
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 26, 2020; 8(18): 4272-4279
Published online Sep 26, 2020. doi: 10.12998/wjcc.v8.i18.4272
Lymphoplasmacyte-rich meningioma with atypical cystic-solid feature: A case report
Kang-Chen Gu, Yang Wan, Li Xiang, Long-Sheng Wang, Wen-Jun Yao
Kang-Chen Gu, Li Xiang, Long-Sheng Wang, Wen-Jun Yao, Department of Radiology, The Second Affiliated Hospital of Anhui Medical University, Hefei 230601, Anhui Province, China
Yang Wan, Department of Pathology, The Second Affiliated Hospital of Anhui Medical University, Hefei 230601, Anhui Province, China
Author contributions: Gu KC and Yao WJ reviewed the literature and contributed to manuscript drafting; Wan Y was the patient’s pathologist and analyzed the pathological results; Xiang L and Wang LS analyzed and interpreted the imaging findings; Yao WJ was responsible for the revision of the manuscript for important intellectual content; All authors issued final approval for the version to be submitted.
Supported by The Natural Science Foundation of Anhui Medical University, No. 2019xkj031.
Informed consent statement: Informed written consent was obtained from the patient.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Wen-Jun Yao, PhD, Associate Chief Physician, Department of Radiology, The Second Affiliated Hospital of Anhui Medical University, No. 678 Furong Road, Hefei 230601, Anhui Province, China. 979839187@qq.com
Received: April 13, 2020
Peer-review started: April 13, 2020
First decision: July 25, 2020
Revised: August 4, 2020
Accepted: August 20, 2020
Article in press: August 20, 2020
Published online: September 26, 2020
Processing time: 161 Days and 18.5 Hours
Abstract
BACKGROUND

Lymphoplasmacyte-rich meningioma (LPRM) is one of the rarest variants of meningioma and is classified as grade I (benign) tumor. It is characterized by abundant infiltrates of lymphocytes and plasma cells. Here, we report an extremely rare case of LPRM with an atypical imaging finding of multiple cysts around a solid mass.

CASE SUMMARY

The patient was a 36-year-old man with intermittent headache, dizziness, and vomiting for 2 years. Computed tomography and magnetic resonance imaging presented a cystic solid mass in the right frontal lobe with heavy peritumoral edema and obvious contrast enhancement. The patient was treated with right frontotemporal craniotomy, and gross total resection of the tumor was achieved without adjuvant therapy. There was no clinical or neuroradiological evidence of recurrent or residual tumor for 3 years after initial surgery.

CONCLUSION

LPRM is one of the rarest variants of meningioma. Although, the mass of this case had common features, multiple cysts with nonuniform size and thin wall around the solid part are uncommon imaging finding, increasing the rate of misdiagnosis. The definitive diagnosis of LPRM relies on histopathological findings.

Keywords: Lymphoplasmacyte-rich meningioma; Lymphocyte; Plasmacyte; Computed tomography; Magnetic resonance imaging; Case report

Core Tip: Lymphoplasmacyte-rich meningioma (LPRM) is one of the rarest variants of meningioma. A case of LPRM is presented here with atypical imaging finding of multiple cysts around a solid mass, which has been reported even more rarely. In computed tomography and magnetic resonance imaging findings, the mass had common features: An irregular shape, unclear boundary with neighboring brain tissue, heavy peritumoral brain edema, significant enhancement of the solid part, and dural tail sign. Multiple cysts with nonuniform size and thin wall around the solid part are uncommon imaging finding, increasing the rate of misdiagnosis. The definitive diagnosis of LPRM relies on histopathological findings.