Published online Sep 6, 2019. doi: 10.12998/wjcc.v7.i17.2605
Peer-review started: March 18, 2019
First decision: July 30, 2019
Revised: August 4, 2019
Accepted: August 20, 2019
Article in press: August 20, 2019
Published online: September 6, 2019
Organ-associated pseudosarcomatous myofibroblastic proliferation (PMP) is a very rare disorder. In the urogenital tract, PMP preferentially involves the urinary bladder; kidney involvement is rare. Here, we report a rare case of PMP with ossification in the lower pole of the kidney, which mimics urothelial carcinoma or an osteogenic tumor.
A Chinese man was admitted to our hospital due to intermittent hematuria for more than 1 mo. Enhanced renal computed tomography revealed a mass in the left renal pelvis and upper ureter. The preoperative clinical diagnosis was renal pelvic carcinoma, determined by imaging examination and biopsy. After a standard preparation for surgery, the patient underwent retroperitoneoscopic radical nephroureterectomy. The operative findings were an extensive renal tumor (6 cm × 4.5 cm × 4.5 cm) invading the lower pole of the kidney and upper ureter. The final pathological diagnosis was organ-associated PMP with ossification. After 6-mo follow-up, no recurrence or metastasis was found.
This case of PMP was unusual for its mimicking renal pelvic carcinoma in imaging examinations, making biopsy necessary.
Core tip: Organ-associated pseudosarcomatous myofibroblastic proliferation (PMP) in the urinary bladder has been reported. However, it rarely occurs in the kidney and no previous case of renal PMP with ossification have been reported. In this case report, the preoperative clinical diagnosis of renal pelvic carcinoma was made by imaging examination and biopsy. Retroperitoneoscopic radical nephroureterectomy was performed, and the final pathological diagnosis was organ-associated PMP with ossification. This case may help us to better understand this disease with regards to the related clinical manifestations, laboratory examination, imaging and pathologic results.