Published online Jun 16, 2017. doi: 10.12998/wjcc.v5.i6.234
Peer-review started: February 7, 2017
First decision: March 7, 2017
Revised: March 15, 2017
Accepted: April 23, 2017
Article in press: April 24, 2017
Published online: June 16, 2017
Synthetic cannabinoids have become a common drug of abuse in recent years and their toxicities have come to light as well. They are known to be notorious for the kidneys, with acute tubular necrosis, acute interstitial nephritis and rhabdomyolysis induced renal injury being the frequent nephrotoxic outcomes in users. We report a case of bilateral renal cortical necrosis, leading to irreversible renal damage and lifelong dialysis dependency.
Core tip: Renal cortical necrosis is a debilitating condition and has a number of causes, in our case a 47 years old female suffered from this condition after smoking synthetic cannabinoids (SCBs) which are a new form of synthetic illicit designer drugs. The patient presented with nausea for 5 d along with anuria for past 24 h before presentation. On laboratory findings the patient had thrombocytopenia while clinically the patient had thrombotic microangiopathy which leads to bilateral renal cortical necrosis. Patient was placed permanently on hemodialysis. Thus awareness needs to be dispersed about potential effects of SCBs.