Published online Sep 16, 2016. doi: 10.12998/wjcc.v4.i9.302
Peer-review started: January 24, 2016
First decision: April 18, 2016
Revised: May 8, 2016
Accepted: July 14, 2016
Article in press: July 16, 2016
Published online: September 16, 2016
Gliosarcoma is rare central nervous system tumour and a variant of glioblastoma multiforme with bimorphic histological pattern of glial and sarcomatous differentiation. It occurs in elderly between 5th and 6th decades of life and extremely rare in children. It is highly aggressive tumour and managed like glioblastoma multiforme. A 12-year-old female child presented with complaints of headache and vomiting from 15 d and blurring of vision from 3 d. Magnetic resonance imaging of brain shows heterogeneous mass in right parieto-occipital cortex. A right parieto-occipito-temporal craniotomy with complete excision of mass revealed a primary glioblastoma on histopathological investigation. Treatment consists of maximum surgical excision followed by adjuvant radiotherapy. The etiopathogenesis, treatment modalities and prognosis is discussed. The available literature is also reviewed.
Core tip: We report a rare case of primary gliosarcoma right parieto-occipital cortex in a 12-year-old girl with review of available literature. The etiopathogenesis, treatment modalities and prognosis is discussed in view of the literature.