Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Feb 16, 2024; 12(5): 995-1003
Published online Feb 16, 2024. doi: 10.12998/wjcc.v12.i5.995
Imaging, pathology, and diagnosis of solitary fibrous tumor of the pancreas: A case report and review of literature
Wen-Wen Wang, Shu-Ping Zhou, Xiang Wu, Luo-Luo Wang, Yi Ruan, Jun Lu, Hai-Li Li, Xu-Ling Ni, Li-Li Qiu, Xin-Hua Zhou
Wen-Wen Wang, Xiang Wu, Luo-Luo Wang, Yi Ruan, Li-Li Qiu, Xin-Hua Zhou, Department of Hepatobiliary and Pancreatic Surgery, The Affiliated Li Huili Hospital, Ningbo University School of Medicine, Ningbo 315000, Zhejiang Province, China
Shu-Ping Zhou, Ningbo College of Health Sciences, Ningbo College of Health Sciences, Ningbo 315000, Zhejiang Province, China
Xiang Wu, Health Science Center, Ningbo University, Ningbo 315000, Zhejiang Province, China
Jun Lu, Department of Hepatobiliary and Pancreatic Surgery, The Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, Zhejiang Province, China
Hai-Li Li, Xu-Ling Ni, Department of Diagnosis, Ningbo Diagnostic Pathology Center, Ningbo 315000, Zhejiang Province, China
Co-first authors: Wen-Wen Wang and Xiang Wu.
Co-corresponding authors: Xin-Hua Zhou and Li-Li Qiu.
Author contributions: Wang WW, Zhou SP and Wu X, investigation, data curation, writing-original draft; Wang LL investigation, provide image pictures; Ruan Y investigation, funding acquisition, medical history collection; Lu J investigation, supervision; Li HL pathology to provide; Ni XL pathology to provide; Qiu LL and Zhou XH resources, writing-review and editing, supervision, project administration funding acquisition; all authors read and approved the final manuscript. The author contributions of Wang WW and Wu X as co-first authors, Qiu LL and Zhou XH as corresponding authors are as follows: Wang WW and Wu X are co-first authors because they made equal contributions to the research and were involved in all stages of the study, from design to data collection and analysis. They both contributed significantly to the writing of the manuscript and are responsible for the accuracy and validity of the results reported. Qiu LL and Zhou XH are corresponding authors because they supervised the research project, provided guidance and expertise throughout the study, and ensured the quality and reliability of the data presented. As senior researchers, they are responsible for the overall content and implications of the study and act as points of contact for further information or queries.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xin-Hua Zhou, Doctor, PhD, Chief Doctor, Doctor, Department of Hepatobiliary and Pancreatic Surgery, The Affiliated Li Huili Hospital, Ningbo University School of Medicine, No. 1111 Jiangnan Road, Yinzhou District, Ningbo 315000, Zhejiang Province, China. zhouxinhua1002@163.com
Received: October 13, 2023
Peer-review started: October 13, 2023
First decision: November 28, 2023
Revised: December 1, 2023
Accepted: January 18, 2024
Article in press: January 18, 2024
Published online: February 16, 2024
Abstract
BACKGROUND

A solitary fibrous tumor (SFT) is often located in the pleura, while SFT of the pancreas is extremely rare. Here, we report a case of SFT of the pancreas and discuss imaging, histopathology, and immunohistochemistry for accurate diagnosis and treatment.

CASE SUMMARY

A 54-year-old man presented to our hospital with pancreatic occupancy for over a month. There were no previous complaints of discomfort. His blood pressure was normal. Blood glucose, tumor markers, and enhanced computed tomography (CT) suggested a malignant tumor. Because the CT appearance of pancreatic cancer varies, we could not confirm the diagnosis; therefore, we performed endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB). Pathology and immunohistochemistry were consistent with SFT of the pancreas. The postoperative pathology and immunohistochemistry were consistent with the puncture results. The patient presented for a follow-up examination one month after discharge with no adverse effects.

CONCLUSION

Other diseases must be excluded in patients with a pancreatic mass that cannot be diagnosed. CT and pathological histology have diagnostic value for pancreatic tumors. Endoscopic puncture biopsy under ultrasound can help diagnose pancreatic masses that cannot be diagnosed preoperatively. Surgery is an effective treatment for SFT of the pancreas; however, long-term follow-up is strongly recommended because of the possibility of malignant transformation of the tumor.

Keywords: Pancreas, Neoplasm fibrous tumor, Endoscopic ultrasound-guided fine-needle biopsy, Treatment, Case report

Core Tip: We need to be more vigilant for indeterminate pancreatic masses, and then computed tomography and histopathology can play a very important role in clinical diagnosis. Surgery is an effective treatment for solitary fibrous tumor of the pancreas; however, long-term follow-up is strongly recommended because of the possibility of malignant transformation of the tumor.