Fan CY, Zhang CG, Zhang PS, Chen Y, He JQ, Yin H, Gong XJ. Acute diquat poisoning case with multiorgan failure and a literature review: A case report. World J Clin Cases 2023; 11(27): 6565-6572 [PMID: 37900248 DOI: 10.12998/wjcc.v11.i27.6565]
Corresponding Author of This Article
Xiao Jie Gong, MD, Doctor, Emergency Department, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, No. 168 Litang Road, Changping District, Beijing 102218, China. gxja00812@btch.edu.cn
Research Domain of This Article
Emergency Medicine
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Sep 26, 2023; 11(27): 6565-6572 Published online Sep 26, 2023. doi: 10.12998/wjcc.v11.i27.6565
Acute diquat poisoning case with multiorgan failure and a literature review: A case report
Chun-Yang Fan, Chen-Guang Zhang, Peng-Shu Zhang, Yu Chen, Jian-Qiang He, He Yin, Xiao-Jie Gong
Chun-Yang Fan, Chen-Guang Zhang, Peng-Shu Zhang, Yu Chen, Jian-Qiang He, He Yin, Xiao-Jie Gong, Emergency Department, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing 102218, China
Author contributions: Fan CY and Zhang CG contributed to manuscript writing and editing, and data collection; He JQ and He Y performed the literature review, collected all the data related to the case report; Zhang PS and Chen Y contributed to conceptualization and supervision; and all authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that there is no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiao Jie Gong, MD, Doctor, Emergency Department, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, No. 168 Litang Road, Changping District, Beijing 102218, China. gxja00812@btch.edu.cn
Received: June 6, 2023 Peer-review started: June 6, 2023 First decision: August 4, 2023 Revised: August 11, 2023 Accepted: August 25, 2023 Article in press: August 25, 2023 Published online: September 26, 2023 Processing time: 103 Days and 7.7 Hours
Abstract
BACKGROUND
With the withdrawal of paraquat from the market, diquat is widely used, so the treatment of diquat poisoning has become one of the focuses of emergency poisoning diagnosis and treatment.
CASE SUMMARY
We studied the case of a 17-year-old male patient who drank 200 mL (20 g/100 mL) of diquat solution two hours before arriving at the hospital. Despite the use of treatments such as gastric lavage, hemoperfusion, continuous hemodialysis, glucocorticoids, and organ support, the patient’s condition rapidly progressed to multiorgan failure, and he died 23.5 h after admission.
CONCLUSION
We summarized the clinical characteristics and treatment strategies of diquat poisoning through this case and performed a literature review to provide a basis and direction for clinical treatment.
Core Tip: The clinical manifestations of diquat poisoning are mainly local mucosal injury and multiple organ damage. The earlier organ function damage occurs, and the more systems are involved, the poorer the prognosis is. In addition, the prognosis of patients is significantly correlated with the poisoning dose, and fulminant poisoning has a high mortality rate. In the treatment of patients, early and adequate removal of toxins is the focus of treatment, and comprehensive and systematic organ function evaluation and support is also an important part of treatment.