Case Report
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. May 16, 2023; 11(14): 3362-3368
Published online May 16, 2023. doi: 10.12998/wjcc.v11.i14.3362
Primary rectal mucosa-associated lymphoid tissue lymphoma treated with only endoscopic submucosal dissection: A case report
Wan-Sik Lee, Myung-Giun Noh, Young-Eun Joo
Wan-Sik Lee, Young-Eun Joo, Department of Internal Medicine, Chonnam National University Medical School, Hwasun-eup 58128, South Korea
Myung-Giun Noh, Department of Pathology, Chonnam National University Medical School, Hwasun-eup 58128, South Korea
Author contributions: Lee WS, Noh MG, Joo YE contributed to manuscript writing and editing and data collection; Joo YE contributed to conceptualization and supervision; all authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Young-Eun Joo, MD, PhD, Professor, Department of Internal Medicine, Chonnam National University Medical School, 264 Seoyang-ro, Hwasun-eup, Hwasun-gun, Hwasun-eup 58128, South Korea. yejoo@chonnam.ac.kr
Received: March 6, 2023
Peer-review started: March 6, 2023
First decision: March 24, 2023
Revised: April 3, 2023
Accepted: April 12, 2023
Article in press: April 12, 2023
Published online: May 16, 2023
Processing time: 71 Days and 0.1 Hours
Abstract
BACKGROUND

Mucosa-associated lymphoid tissue (MALT) lymphoma is a distinct subtype of non-Hodgkin B cell lymphoma that mostly involves the gastrointestinal tract. The stomach is the most commonly affected site whereas colorectal involvement occurs very rarely. Given its rarity, the management and clinical outcome of colorectal MALT lymphoma are not well established yet.

CASE SUMMARY

From the superficial capillary bed in the lower rectum. Endoscopic ultrasonography showed homogenous hypoechoic lesions in the deep mucosal layer. Endoscopic submucosal dissection (ESD) was done for accurate histologic diagnosis and treatment and both the rectal lesions were completely removed en bloc and subsequently diagnosed as primary rectal MALT lymphoma. Herein, we report a case of primary rectal MALT lymphoma in a 68-year-old woman that was treated by only ESD, and the 12-month follow-up revealed no tumour recurrence.

CONCLUSION

These results of our case and previous reports suggest that endoscopic resection alone may be a feasible and safe treatment for primary colorectal MALT lymphoma and allows organ preservation.

Keywords: Rectum; Mucosa-associated lymphoid tissue lymphoma; Endoscopic submucosal dissection

Core Tip: Colorectal involvement of Mucosa-associated lymphoid tissue (MALT) lymphoma occurs rarely and the management of colorectal MALT lymphoma are not well established yet. We report a rare case of colorectal MALT lymphoma treated with endoscopic resection alone. To date, only six cases of primary colorectal MALT lymphomas treated with endoscopic resection alone, including our patient, have been documented in the medical literature. Among the reported cases, there was no recurrence during follow-up. These results of our case and previous reports suggest that endoscopic resection alone may be a feasible and safe treatment for primary colorectal MALT lymphoma and allows organ preservation.