Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 6, 2022; 10(19): 6716-6721
Published online Jul 6, 2022. doi: 10.12998/wjcc.v10.i19.6716
Concurrent alcoholic cirrhosis and malignant peritoneal mesothelioma in a patient: A case report
Liang Liu, Xiao-Yan Zhu, Wen-Jie Zong, Chuan-Lian Chu, Jing-Yu Zhu, Xing-Jie Shen
Liang Liu, Xiao-Yan Zhu, Wen-Jie Zong, Chuan-Lian Chu, Jing-Yu Zhu, Xing-Jie Shen, Department of Gastroenterology, Central Hospital Affiliated to Shandong First Medical University, Jinan 250011, Shandong Province, China
Liang Liu, Xiao-Yan Zhu, Wen-Jie Zong, Chuan-Lian Chu, Jing-Yu Zhu, Xing-Jie Shen, Department of Gastroenterology, Jinan Clinical Research Center for Digestive Diseases, Jinan 250011, Shandong Province, China
Author contributions: Liu L, Zhu XY, Zong WJ contributed equally to this work; Shen XJ, Zhu XY, Zong WJ, Chu CL and Liu L collected patient data; Liu L drafted the manuscript; Chu CL and Zhu JY revised the manuscript; all authors read and approved the final manuscript.
Supported by Shandong Province Medical and Health Science and Technology Development Plan, No. 202003030878.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xing-Jie Shen, MD, Chief Doctor, Department of Gastroenterology, Central Hospital Affiliated to Shandong First Medical University, No. 105 Jiefang Road, Lixia District, Jinan 250011, Shandong Province, China. starshen@sina.com
Received: January 24, 2022
Peer-review started: January 24, 2022
First decision: March 23, 2022
Revised: March 28, 2022
Accepted: May 8, 2022
Article in press: May 8, 2022
Published online: July 6, 2022
Abstract
BACKGROUND

Malignant peritoneal mesothelioma (MPM) originates from the mesothelial and subcutaneous cells of the abdominal cavity. Its diagnose is difficult due to its nonspecific and vague symptoms, and it should be differentiated from alcoholic cirrhosis and liver and pancreatic cancers. Misdiagnosis and missed diagnosis can easily occur when MPM presents with other diseases. To the best of our knowledge, no case of MPM concurrent with alcoholic cirrhosis has been reported.

CASE SUMMARY

A 63-year-old man presented to our hospital with abdominal distension for 20days. He had a history of alcohol consumption for nearly 30 years and no history of special drug use or toxic exposure. After treatment for alcoholic cirrhosis in a community hospital, his symptoms did not improve significantly. The patient underwent exploratory laparotomy and surgical resection. Pathologic examination showed an epithelioid MPM. He was treated with chemotherapy and intraperitoneal hyperthermic perfusion after surgery. Currently, he is in a stable condition and tumor recurrence has not occurred.

CONCLUSION

Misdiagnosis and missed diagnosis of MPM can easily occur because of its insidious onset. Therefore, there is a need to understand. MPM in clinical practice, make the correct diagnosis, and provide timely and effective treatment.

Keywords: Malignant peritoneal mesothelioma, Abdominal distension, Ascites, Cirrhosis, Computed tomography, Case report

Core Tip: Malignant peritoneal mesothelioma (MPM) is a rare disease with nonspecific and vague symptoms. MPM concurrent with alcoholic cirrhosis has not been reported previously. We report the case of a 63-year-old man who had abdominal distension and was initially diagnosed with alcoholic cirrhosis. His symptoms did not improve significantly after treatment for the cirrhosis. The patient then underwent exploratory laparotomy, and pathologic examination showed an epithelioid MPM. Misdiagnosis and missed diagnosis of MPM is commom because of its insidious onset. Clinicians should be aware of the disease and make a correct diagnosis so as to provide patients with timely and effective treatment. MPM concurrent with alcoholic cirrhosis is rare and requires further study.