Published online Jul 6, 2022. doi: 10.12998/wjcc.v10.i19.6702
Peer-review started: January 23, 2022
First decision: March 23, 2022
Revised: April 1, 2022
Accepted: May 8, 2022
Article in press: May 8, 2022
Published online: July 6, 2022
Endometrial cancer (EC) is a common gynecological malignancy, but metastasis to the abdominal wall is extremely rare. Therefore, an appropriate treatment approach for large metastatic lesions with infection remains a great challenge.
We report the case of a 65-year-old woman who developed abdominal metastasis of endometrioid adenocarcinoma, as defined by International Obstetrics and Gynecology stage II, in which the lesion was complicated by infection. A right hemicolectomy was performed for colon metastasis in relation to her initial gynecological cancer 3 years ago. When admitted to our department, a complete resection of the giant abdominal wall lesion was performed, and a Bard composite mesh was used to reconstruct the abdominal wall. A local flap was used to close the resultant large defect in the external covering of the abdomen. The patient underwent chemotherapy following cytoreductive surgery. Pathology revealed metastasis of EC, and molecular subtyping showed copy number high of TP53 mutation, implying a poor prognosis.
When EC patients develop giant abdominal wall metastasis, a plastic surgeon should be included before contemplating resection of tumors.
Core Tip: This report presents a rare case of endometrioid adenocarcinoma with extensive abdominal wall metastasis complicated by infection, and highlights the design of the reconstruction of the abdominal wall after resection. A plastic surgeon should be included in the planning before contemplating resection of large tumors.