Observational Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Transplant. Nov 18, 2022; 12(11): 365-377
Published online Nov 18, 2022. doi: 10.5500/wjt.v12.i11.365
Effects of an active lifestyle on the physical frailty of liver transplant candidates
Ilias Marios Oikonomou, Emmanouil Sinakos, Nikolaos Antoniadis, Ioannis Goulis, Olga Giouleme, Maria Anifanti, Georgios Katsanos, Konstantina-Eleni Karakasi, Georgios Tsoulfas, Evangelia Kouidi
Ilias Marios Oikonomou, Nikolaos Antoniadis, Georgios Katsanos, Konstantina-Eleni Karakasi, Georgios Tsoulfas, Department of Transplant Surgery, Aristotle University of Thessaloniki, Thessaloniki 54642, Greece
Emmanouil Sinakos, Ioannis Goulis, The Fourth Department of Internal Medicine, Aristotle University of Thessaloniki, Thessaloniki 54642, Greece
Olga Giouleme, The Second Propaedeutic Department of Internal Medicine, Aristotle University of Thessaloniki, Thessaloniki 54642, Greece
Maria Anifanti, Evangelia Kouidi, Laboratory of Sports Medicine, Aristotle University of Thessaloniki, Thessaloniki 57001, Greece
Author contributions: Oikonomou IM and Kouidi E designed the research study; Oikonomou IM, Sinakos E, Antoniadis N, Goulis I, Giouleme O, Anifanti M, Katsanos G, and Tsoulfas G performed the research; Oikonomou IM and Karakasi KE analyzed the data and results; Oikonomou IM wrote the manuscript; and all authors have read and approved the final manuscript.
Institutional review board statement: The study was reviewed and approved by the Aristotle University of Thessaloniki Institutional Review Board (Approval No. 65/2021).
Informed consent statement: All patients participating in the study provided written and informed consent prior to their inclusion.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: There are no additional data available.
STROBE statement: The authors have read the STROBE Statement checklist of items, and the manuscript was prepared and revised according to the STROBE Statement checklist of things.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ilias Marios Oikonomou, MD, MPhil, Surgeon, Department of Transplant Surgery, Aristotle University of Thessaloniki, 49 Konstantinoupoleos Street, Thessaloniki 54642, Greece. i.m.oikonomou@gmail.com
Received: June 15, 2022
Peer-review started: June 15, 2022
First decision: August 4, 2022
Revised: August 26, 2022
Accepted: October 18, 2022
Article in press: October 18, 2022
Published online: November 18, 2022
Core Tip

Core Tip: This study highlights the importance of regular physical activity and exercise of low and medium intensities in the routine of liver transplant candidates. As liver transplantation is a highly demanding procedure, imposing a significant amount of stress across every system, physical frailty is steadily proving to be a factor of great importance, not only due to its role in mortality prediction but also due to its potential improvement via preoperative interventions.