Startle response and its prepulse modification in health and under different psychopathologies: Could we find any specific patterns?

doi:10.5498/wjp.v15.i8.107791

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Aug 19, 2025 (publication date) through Aug 8, 2025

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Psychiatry. Aug 19, 2025; 15(8): 107791
Published online Aug 19, 2025. doi: 10.5498/wjp.v15.i8.107791

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Figure 1 Brain structures involved in the mechanisms of the acoustic startle response and its prepulse inhibition. Black bar: Main intensive stimulus (pulse); Grey bar: Preceding weak stimulus (prepulse); Triangle: Amplitude of startle response; White wide arrow: Protection of prepulse processing; Black wide arrow: Protection of main stimulus (pulse) processing. Data obtained in humans and rodents using lesion, stimulation and neuroimaging techniques are summarized[4,5,14-17,45,48]. PPI: Prepulse inhibition; ASR: Acoustic startle response.

Citation: Storozheva ZI. Startle response and its prepulse modification in health and under different psychopathologies: Could we find any specific patterns? World J Psychiatry 2025; 15(8): 107791
URL: https://www.wjgnet.com/2220-3206/full/v15/i8/107791.htm
DOI: https://dx.doi.org/10.5498/wjp.v15.i8.107791