Informed consent competency assessment for brain-computer interface clinical research and application in psychiatric disorders: A systematic review

doi:10.5498/wjp.v15.i8.107593

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 15, Issue 8

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (154)

All Articles published online

The chart showing PDF series, HTML series, Figures (1-3) series, Tables (1-3) series.

Item

Count

PDF

HTML

Figures (1-3)

Tables (1-3)

Sum=108

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

Download

Sum=41

Aug 19, 2025 (publication date) through Aug 11, 2025

Times Cited of This Article

Times Cited (0)

Journal Information of This Article

Publication Name

World Journal of Psychiatry

ISSN

2220-3206

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Systematic Reviews

World J Psychiatry. Aug 19, 2025; 15(8): 107593
Published online Aug 19, 2025. doi: 10.5498/wjp.v15.i8.107593

Informed consent competency assessment for brain-computer interface clinical research and application in psychiatric disorders: A systematic review

Jia-Yue Si, Zi-Yan Lin, Di-Ga Gan, Xin-Yang Zhang, Yan-Nan Liu, Yu-Xin Hu, Yan-Ping Bao, Xue-Qin Wang, Hong-Qiang Sun, Xin Yu, Lin Lu

Jia-Yue Si, Di-Ga Gan, Xin-Yang Zhang, Yan-Nan Liu, Yu-Xin Hu, Xue-Qin Wang, Hong-Qiang Sun, Xin Yu, Lin Lu, Department of Psychiatry, Peking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Peking University, Beijing 100191, China

Zi-Yan Lin, Department of Psychology, University of Toronto, Toronto M5S 1A1, Ontario, Canada

Yan-Ping Bao, Department of Epidemiology, National Institute on Drug Dependence and Beijing Key Laboratory of Drug Dependence, Peking University, Beijing 100191, China

Yan-Ping Bao, Department of Epidemiology, School of Public Health, Peking University, Beijing 100191, China

Lin Lu, Department of Psychiatry, Peking-Tsinghua Centre for Life Science and Peking University-International Development Group/McGovern Institute for Brain Research, Peking University, Beijing 100871, China

Co-first authors: Jia-Yue Si and Zi-Yan Lin.

Author contributions: Wang XQ, Si JY and Lin ZY helped plan and carry out the review; Wang XQ and Si JY led in designing the study and writing the manuscript; Si JY, Lin ZY, and Wang XQ had a key role in the study’s main ideas and revising the manuscript; Gan DG ensured that the data used were reliable and drafted the figures; Zhang XY, Liu YN, and Hu YX participated in drafting the manuscript; Bao YP guided and certificated the biostatistics; Sun HQ, Yu X, and Lu L provided comprehensive expertise in reviewing and editing the manuscript; and all authors have carefully reviewed and given their approval for the final manuscript.

Supported by the Ministry of Science and Technology of the People's Republic of China (2021ZD0201900) Project 5, No. 2021ZD0201905, and Capital’s Funds for Health Improvement and Research, No. CFH 2022-2-4115.

Conflict-of-interest statement: There are no conflicts of interest.

PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.

Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Xue-Qin Wang, MD, Associate Professor, Department of Psychiatry, Peking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Peking University, No. 51 Huayuanbei Road, Haidian District, Beijing 100191, China. wangxueqin@bjmu.edu.cn

Received: March 27, 2025
Revised: April 29, 2025
Accepted: July 1, 2025
Published online: August 19, 2025
Processing time: 134 Days and 20.1 Hours

Core Tip

Core Tip: Informed consent among psychiatric patients is a major concern in brain-computer interface (BCI) clinical research. This review identifies informed consent competency (ICC) assessment as the main challenge, particularly in patients with schizophrenia, mood disorders, anorexia nervosa, alcohol dependence, and neurocognitive disorders due to Alzheimer’s disease and Parkinson’s disease. The MacArthur Competence Assessment Tool evaluates four clinical aspects of ICC. Six psychiatric disorders have common and disorder-specific factors and ethical issues related to ICC. The Five-Dimension BCI-specific ICC framework is constructed in psychiatric disorders. Future research should develop dynamic evaluation systems and enhance ICC of psychiatric patients in BCI clinical studies.