Observational Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Aug 19, 2025; 15(8): 106887
Published online Aug 19, 2025. doi: 10.5498/wjp.v15.i8.106887
Global burden of mental disorders in 204 countries and territories results from the Global Burden of Disease Study 2021
Qing-Song Mao, Yu-Xin Guo, Xin-Ling Tian, Hai-Long Zhao, Yu-Zhe Kong
Qing-Song Mao, Hai-Long Zhao, Department of Hepatobiliary Pancreatic Surgery, Banan Hospital Affiliated of Chongqing Medical University, Chongqing 410132, China
Yu-Xin Guo, Xinxiang Medical University, Xinxiang 20000, Henan Province, China
Xin-Ling Tian, Yu-Zhe Kong, Xiangya School of Medicine, Central South University, Changsha 410013, Hunan Province, China
Co-corresponding authors: Hai-Long Zhao and Yu-Zhe Kong.
Author contributions: Mao QS contributed to formal analysis and writing the original draft; Guo YX contributed to data curation; Tian XL contributed to visualization; Zhao HL and Kong YZ edited the manuscript and made equal contributions as co-corresponding authors. All authors approved the final version to publish.
Institutional review board statement: This article is based on a secondary analysis of the Global Burden of Disease database. The Global Burden of Disease database does not contain individual-level data, thus allowing for relevant exemptions.
Informed consent statement: This study was conducted by using data from the Global Burden of Disease Study 2021. In this database, it didn’t contain individual level data. Thus, informed consent wasn’t needed.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: Corresponding authors may provide data upon request.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yu-Zhe Kong, Xiangya School of Medicine, Central South University, No. 172 Tongzipo Road, Changsha 410013, Hunan Province, China. csuyuzhekong@foxmail.com
Received: March 13, 2025
Revised: April 29, 2025
Accepted: June 17, 2025
Published online: August 19, 2025
Processing time: 150 Days and 18.7 Hours
Core Tip

Core Tip: Mental disorders, one of the leading causes of the global health-related burden. Global Disease Burden Study 2021 showed that the burden of mental disorders was still on the rise gradually worldwide. The burden exacerbated by the emergence of the coronavirus disease 2019 pandemic. The mental disorders burden of high-middle socio-demographic index regions and females should be paid more attention.