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World J Psychiatry. Aug 19, 2025; 15(8): 106025
Published online Aug 19, 2025. doi: 10.5498/wjp.v15.i8.106025
Can reinforcement learning effectively prevent depression relapse?
Haewon Byeon
Haewon Byeon, Worker’s Care & Digital Health Lab, Department of Future Technology, Korea University of Technology and Education, Cheonan 31253, South Korea
Author contributions: Byeon H contributed to data interpretation, developed methodology, and manuscript writing.
Supported by the Education and Research Promotion Program of KOREATECH.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Haewon Byeon, PhD, Associate Professor, Worker’s Care & Digital Health Lab, Department of Future Technology, Korea University of Technology and Education, No. 1600 Chungjeol-ro, Cheonan 31253, South Korea. bhwpuma@naver.com
Received: February 14, 2025
Revised: April 7, 2025
Accepted: June 18, 2025
Published online: August 19, 2025
Processing time: 176 Days and 3.1 Hours
Core Tip

Core Tip: Reinforcement learning (RL) holds significant promise in preventing depression relapse by enabling personalized and adaptive mental health interventions. By leveraging advanced machine learning algorithms, RL can analyze behavioral data for early relapse risk detection and optimize treatment strategies tailored to individual needs. This study reviews the existing literature, highlighting RL’s potential to transform mental health care through personalized learning and data-driven decision-making. However, challenges such as algorithmic complexity and ethical considerations must be addressed. Future research should focus on larger-scale studies and interdisciplinary collaboration to establish RL as a viable tool for effective depression management and relapse prevention.