Nutritional psychiatry for hypertensive older adults

doi:10.5498/wjp.v15.i6.106262

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Jun 19, 2025 (publication date) through Jun 26, 2025

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Psychiatry. Jun 19, 2025; 15(6): 106262
Published online Jun 19, 2025. doi: 10.5498/wjp.v15.i6.106262

Nutritional psychiatry for hypertensive older adults

Takahiko Nagamine

Takahiko Nagamine, Department of Psychiatric Internal Medicine, Sunlight Brain Research Center, Hofu 7470066, Yamaguchi, Japan

Author contributions: Nagamine T designed and conceived the study, collected the data, analyzed and interpreted the results, drafted the manuscript, and has read and agreed to the published version of the manuscript.

Conflict-of-interest statement: All authors have no conflicts of interest to declare.

Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Takahiko Nagamine, MD, PhD, Department of Psychiatric Internal Medicine, Sunlight Brain Research Center, 4-13-18 Jiyugaoka, Hofu 7470066, Yamaguchi, Japan. anagamine@yahoo.co.jp

Received: February 21, 2025
Revised: March 28, 2025
Accepted: April 3, 2025
Published online: June 19, 2025
Processing time: 98 Days and 8.5 Hours

Core Tip

Core Tip: In hypertensive older adults, body mass index (BMI), serum hemoglobin, and serum albumin levels have been identified as independent protective factors for cognitive function. Conversely, alkaline phosphatase (ALP) has been associated with cognitive decline. BMI, hemoglobin, and albumin are commonly used as indicators of nutritional status, and poor nutritional status has been linked to poorer cognitive function. While ALP itself does not directly impact cognitive function, it serves as a marker of overall status and can predict cognitive decline.