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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Jun 19, 2025; 15(6): 105222
Published online Jun 19, 2025. doi: 10.5498/wjp.v15.i6.105222
Published online Jun 19, 2025. doi: 10.5498/wjp.v15.i6.105222
Perceived stress, risk factors and prognostic monitoring loci for the development of depression
Xuan Li, Xiao-Shuang Zhang, Department of General Surgery, Linyi Hospital of Traditional Chinese Medicine, Linyi 276003, Shandong Province, China
Wei Zhao, Department of Otolaryngology, Linyi Hospital of Traditional Chinese Medicine, Linyi 276003, Shandong Province, China
Yu-Han Wei, School of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, Shandong Province, China
Yong Zhu, Department of Emergency Surgery, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250014, Shandong Province, China
Xu-Hao Li, School of Acupuncture and Tuina, Shandong University of Traditional Chinese Medicine, Jinan 250355, Shandong Province, China
Co-first authors: Xuan Li and Wei Zhao.
Co-corresponding authors: Yong Zhu and Xu-Hao Li.
Author contributions: Li X and Zhang XS wrote the manuscript; Zhao W and Wei YH revised the manuscript; Zhu Y and Li XH designed the overall concept and outline of the manuscript; all authors contributed to this paper and have approved the final version of the manuscript.
Conflict-of-interest statement: There are no conflicts of interest in this study.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xu-Hao Li, MD, PhD, Assistant Professor, School of Acupuncture and Tuina, Shandong University of Traditional Chinese Medicine, No. 4655 University Road, Jinan 250355, Shandong Province, China. l1xuhao2022@163.com
Received: January 15, 2025
Revised: March 19, 2025
Accepted: March 20, 2025
Published online: June 19, 2025
Processing time: 134 Days and 21 Hours
Revised: March 19, 2025
Accepted: March 20, 2025
Published online: June 19, 2025
Processing time: 134 Days and 21 Hours
Core Tip
Core Tip: In this editorial, we provide an overview of the relationship between stress and depression. The potential role of stress in the diagnosis and prognostic monitoring of depression is analysed through the existing literature with the aim of providing new perspectives on the prevention, diagnosis and treatment of depression. This article will further emphasise the importance of uncovering stress biomarkers in depression.