Case Control Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. May 19, 2025; 15(5): 103628
Published online May 19, 2025. doi: 10.5498/wjp.v15.i5.103628
Predictors of poor prognosis in long-term survivors of differentiated thyroid cancer with psychiatric disorders
Jin-Liang Jia, Ji-Hua Han, Rui Pang, Wen Bi, Bo Liu, Kun Yang
Jin-Liang Jia, Ji-Hua Han, Rui Pang, Wen Bi, Bo Liu, Department of Head and Neck Surgery, Harbin Medical University Cancer Hospital, Harbin 150081, Heilongjiang Province, China
Kun Yang, Department of Anesthesiology, Harbin Medical University Affiliated Cancer Hospital, Harbin 150081, Heilongjiang Province, China
Author contributions: Jia JL conceptualized and designed the research study, analyzed the data, and contributed to the writing of the manuscript; Han JH conducted the research, collected and managed the data, and participated in the analysis; Pang R contributed to the development of analytical tools and reagents, and assisted in data interpretation; Bi W provided new reagents and analytical tools, and co-wrote the manuscript; Liu B assisted in data collection and analysis, and contributed to the interpretation of results; Yang K supervised the study, provided critical feedback, and contributed to the final editing of the manuscript; all authors reviewed and approved the final version of the manuscript.
Institutional review board statement: The study was reviewed and approved by the Harbin Medical University Cancer Hospital Institutional Review Board.
Informed consent statement: All subjects understood and agreed to the study protocol and voluntarily provided written informed consent.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
STROBE statement: The authors have read the STROBE Statement—a checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-a checklist of items.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kun Yang, Associate Chief Physician, Department of Anesthesiology, Harbin Medical University Cancer Hospital, No. 150 Haping Road, Nangang District, Harbin 150081, Heilongjiang Province, China. 13804556449@163.com
Received: February 12, 2025
Revised: March 14, 2025
Accepted: April 8, 2025
Published online: May 19, 2025
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Core Tip

Core Tip: The innovative and significant finding of this study is that the combination of tumour diameter, extra-glandular infiltration, serum free T4 levels, and total bilirubin serves as an independent risk factor for poor prognosis in patients with psychiatric disorders and long-term differentiated thyroid cancer, providing higher predictive value for patient prognosis and serving as a basis for developing a reasonable prognostic management plan in clinical practice.