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For: Stoyanov D, Maes MH. How to construct neuroscience-informed psychiatric classification? Towards nomothetic networks psychiatry. World J Psychiatr 2021; 11(1): 1-12 [PMID: 33511042 DOI: 10.5498/wjp.v11.i1.1]
URL: https://www.wjgnet.com/2220-3206/full/v11/i1/1.htm
Number Citing Articles
1
Michael Maes. The Gold Standard Diagnosis of Schizophrenia is Counterproductive: Towards Quantitative Research and Diagnostic Algorithmic Rules (RADAR) and their Derived Qualitative Distinct ClassesCurrent Topics in Medicinal Chemistry 2024; 24(20) doi: 10.2174/0115680266295129240415120646
2
Michael Maes, Ketsupar Jirakran, Asara Vasupanrajit, Mengqi Niu, Bo Zhou, Drozdstoj St. Stoyanov, Chavit Tunvirachaisakul. The recurrence of illness (ROI) index is a key factor in major depression that indicates increasing immune-linked neurotoxicity and vulnerability to suicidal behaviorsPsychiatry Research 2024; 339 doi: 10.1016/j.psychres.2024.116085
3
Michael Maes, George Anderson. False Dogmas in Schizophrenia Research: Toward the Reification of Pathway Phenotypes and Pathway ClassesFrontiers in Psychiatry 2021; 12 doi: 10.3389/fpsyt.2021.663985
4
Rositsa Paunova, Sevdalina Kandilarova, Anna Todeva-Radneva, Adeliya Latypova, Ferath Kherif, Drozdstoy Stoyanov. Application of Mass Multivariate Analysis on Neuroimaging Data Sets for Precision Diagnostics of DepressionDiagnostics 2022; 12(2) doi: 10.3390/diagnostics12020469
5
Yee Ling Chan, Cyrus S.H. Ho, Gabrielle W.N. Tay, Trevor W.K. Tan, Tong Boon Tang. MicroRNA classification and discovery for major depressive disorder diagnosis: Towards a robust and interpretable machine learning approachJournal of Affective Disorders 2024; 360 doi: 10.1016/j.jad.2024.05.066
6
Irene Suilan Zeng, Junxiang Hao, Mandie Foster, Kelly Marie Jones. Path and Bayesian network analyses in the complex design of a well-being survey via New Zealand’s Integrated Data InfrastructureFrontiers in Psychiatry 2026; 17 doi: 10.3389/fpsyt.2026.1826907
7
Hasan Najah Smesam, Hasan Abbas Qazmooz, Sinan Qayes Khayoon, Abbas F. Almulla, Hussein Kadhem Al-Hakeim, Michael Maes. Pathway Phenotypes Underpinning Depression, Anxiety, and Chronic Fatigue Symptoms Due to Acute Rheumatoid Arthritis: A Precision Nomothetic Psychiatry AnalysisJournal of Personalized Medicine 2022; 12(3) doi: 10.3390/jpm12030476
8
Michael Maes, Muanpetch Rachayon, Ketsupar Jirakran, Pimpayao Sodsai, Siriwan Klinchanhom, Monojit Debnath, Agnieska Basta-Kaim, Marta Kubera, Abbas F. Almulla, Atapol Sughondhabirom. Adverse Childhood Experiences Predict the Phenome of Affective Disorders and These Effects Are Mediated by Staging, Neuroimmunotoxic and Growth Factor ProfilesCells 2022; 11(9) doi: 10.3390/cells11091564
9
Drozdstoy S. Stoyanov. Endophenotypes and Pathway Phenotypes in Neuro-psychiatry: Crossdisciplinary Implications for DiagnosisCNS & Neurological Disorders - Drug Targets 2023; 22(2) doi: 10.2174/187152732202220914125530
10
Drozdstoy Stoyanov. Advances in the Diagnosis and Management of PsychosisDiagnostics 2023; 13(9) doi: 10.3390/diagnostics13091517
11
Marcin Rządeczka, Maciej Wodziński, Marcin Moskalewicz. Cognitive biases as an adaptive strategy in autism and schizophrenia spectrum: the compensation perspective on neurodiversityFrontiers in Psychiatry 2023; 14 doi: 10.3389/fpsyt.2023.1291854
12
Michael Maes. Major neurocognitive psychosis: a novel schizophrenia endophenotype class that is based on machine learning and resembles Kraepelin’s and Bleuler’s conceptionsActa Neuropsychiatrica 2023; 35(3) doi: 10.1017/neu.2022.32
13
Nikolay Mehterov, Danail Minchev, Maria Gevezova, Victoria Sarafian, Michael Maes. Interactions Among Brain-Derived Neurotrophic Factor and Neuroimmune Pathways Are Key Components of the Major Psychiatric DisordersMolecular Neurobiology 2022; 59(8) doi: 10.1007/s12035-022-02889-1
14
Michael Maes. Precision Nomothetic Medicine in Depression Research: A New Depression Model, and New Endophenotype Classes and Pathway Phenotypes, and A Digital SelfJournal of Personalized Medicine 2022; 12(3) doi: 10.3390/jpm12030403
15
Drozdstoy Stoyanov. The Anxious Brain: The Influence of Stress on the Nervous SystemBrain Sciences 2024; 14(6) doi: 10.3390/brainsci14060597
16
Jonas Daub, Geva A. Brandt, Sebastian Volkmer, Georg Northoff, Dusan Hirjak. Arthur Schopenhauer: An underappreciated philosopher in psychiatry and his applied epistemology of body and self- experienceSchizophrenia Research 2024; 267 doi: 10.1016/j.schres.2024.04.019
17
Subho Chakrabarti. Bipolar disorder in the International Classification of Diseases-Eleventh version: A review of the changes, their basis, and usefulnessWorld Journal of Psychiatry 2022; 12(12): 1335-1355 doi: 10.5498/wjp.v12.i12.1335
18
Katarina Vesic, Aleksandar Gavrilovic, Nataša R Mijailović, Milica M Borovcanin. Neuroimmune, clinical and treatment challenges in multiple sclerosis-related psychosesWorld Journal of Psychiatry 2023; 13(4): 161-170 doi: 10.5498/wjp.v13.i4.161
19
Diyana Najar, Julian Dichev, Drozdstoy Stoyanov. Towards New Methodology for Cross-Validation of Clinical Evaluation Scales and Functional MRI in PsychiatryJournal of Clinical Medicine 2024; 13(15) doi: 10.3390/jcm13154363
20
Mengqi Niu, Chen Chen, Michael Maes. A nomothetic systems framework for mitochondrial DNA copy number in neuropsychiatric disorders: bidirectional two-sample Mendelian randomizationThe European Physical Journal Special Topics 2026;  doi: 10.1140/epjs/s11734-026-02369-w
21
Rana Fadhil Mousa, Hasan Najah Smesam, Hasan Abbas Qazmooz, Hussein Kadhem Al-Hakeim, Michael Maes. A pathway phenotype linking metabolic, immune, oxidative, and opioid pathways with comorbid depression, atherosclerosis, and unstable anginaCNS Spectrums 2022; 27(6) doi: 10.1017/S1092852921000432
22
Olivia M. Dean, Adam J. Walker. Current approaches to precision medicine in psychiatry: Are we just spinning our wheels?European Neuropsychopharmacology 2023; 66 doi: 10.1016/j.euroneuro.2022.10.003
23
Meng Hao, Yue Qin, Yi Li, Yanqing Tang, Zehan Ma, Jingze Tan, Li Jin, Fei Wang, Xiaohong Gong. Metabolome subtyping reveals multi-omics characteristics and biological heterogeneity in major psychiatric disordersPsychiatry Research 2023; 330 doi: 10.1016/j.psychres.2023.115605
24
Michael Maes, Abbas F. Almulla, Asara Vasupanrajit, Ketsupar Jirakran, Chavit Tunvirachaisakul, Annabel Maes, Prangwalai Chanchaem, Pavit Klomkliew, Sunchai Payungporn, Yingqian Zhang. Functional shotgun metagenomic insights into gut microbial pathway and enzyme disruptions linking metabolism, affect, cognition, and suicidal ideation in major depressive disorderActa Neuropsychiatrica 2026; 38 doi: 10.1017/neu.2026.10056
25
Daniel Montero-Espinoza. Mental disorders in focusPhilosophical Psychology 2024; 37(3) doi: 10.1080/09515089.2024.2327812
26
Teodora M. Gencheva, Bozhidar V. Valkov, Sevdalina S. Kandilarova, Michael H. J. Maes, Drozdstoy S. Stoyanov. Diagnostic value of structural, functional and effective connectivity in bipolar disorderActa Psychiatrica Scandinavica 2025; 151(3) doi: 10.1111/acps.13742
27
Jianqing Qiu, Ting Zhu, Ke Qin, Wei Zhang. The interaction network and potential clinical effectiveness of dimensional psychopathology phenotyping based on EMR: a Bayesian network approachBMC Psychiatry 2025; 25(1) doi: 10.1186/s12888-025-06510-2
28
Drozdstoy Stoyanov, Katrin Aryutova, Sevdalina Kandilarova, Rositsa Paunova, Zlatoslav Arabadzhiev, Anna Todeva-Radneva, Stefan Kostianev, Stefan Borgwardt. Diagnostic Task Specific Activations in Functional MRI and Aberrant Connectivity of Insula with Middle Frontal Gyrus Can Inform the Differential Diagnosis of PsychosisDiagnostics 2021; 11(1) doi: 10.3390/diagnostics11010095
29
Sijian Wang, Lei Tang, Nanqi Huang, Hanyan Wang. The Roles of Long Noncoding RNA in DepressionFrontiers in Bioscience-Landmark 2023; 28(11) doi: 10.31083/j.fbl2811321
30
Hongzhou Wu, Jinming Xiao, Elijah Agoalikum, Talha Imtiaz Baig, Benjamin Becker, Stefania Ferraro, Bharat B. Biswal, Benjamin Klugah-Brown, Michael Maes. Multi-Indicator Entropy Hub Score: A quantitative approach to hub analysis in brain networksNeuroImage 2026; 329 doi: 10.1016/j.neuroimage.2026.121799
31
Diyana Najar, Drozdstoy Stoyanov. Scientific psychiatry within technical reachWorld Journal of Psychiatry 2025; 15(3): 101142 doi: 10.5498/wjp.v15.i3.101142
32
Drozdstoy Stoyanov, Vince D. Calhoun, Georg Northoff. Transdiagnostic Neuroimaging of Depressive and Psychotic Disorders: Applications and MethodsDepression and Anxiety 2025; 2025(1) doi: 10.1155/da/9781201
33
Sevdalina Kandilarova, Drozdstoy St. Stoyanov, Rositsa Paunova, Anna Todeva-Radneva, Katrin Aryutova, Michael Maes. Effective Connectivity between Major Nodes of the Limbic System, Salience and Frontoparietal Networks Differentiates Schizophrenia and Mood Disorders from Healthy ControlsJournal of Personalized Medicine 2021; 11(11) doi: 10.3390/jpm11111110
34
Luxi He, Yinuo He, Yaohan Wang, Xiang-Yao Li, Yun-Rong Lu. Neural mechanisms of non-suicidal self-injury and prospects for precision therapeuticsPsychiatry Research: Neuroimaging 2026; 362 doi: 10.1016/j.pscychresns.2026.112273
35
Drozdstoy Stoyanov, Sevdalina Kandilarova, Ferath Kherif. Computational NeuroscienceNeuromethods 2023; 199 doi: 10.1007/978-1-0716-3230-7_1
36
Hatice Solak, Merve Akkuş, Pınar Aydogan Avşar. Relationship between serum oxidative stress and blood brain barrier parameters in patients with major depressionJournal of Psychiatric Research 2025; 190 doi: 10.1016/j.jpsychires.2025.07.023
37
Michael Maes, Bo Zhou, Ketsupar Jirakran, Asara Vasupanrajit, Patchaya Boonchaya-Anant, Chavit Tunvirachaisakul, Xiaoou Tang, Jing Li, Abbas F. Almulla. Towards a major methodological shift in depression research by assessing continuous scores of recurrence of illness, lifetime and current suicidal behaviors and phenome featuresJournal of Affective Disorders 2024; 350 doi: 10.1016/j.jad.2024.01.150
38
Michael Maes. Computational NeuroscienceNeuromethods 2023; 199 doi: 10.1007/978-1-0716-3230-7_3
39
Drozdstoy Stoyanov, Rositsa Paunova, Julian Dichev, Sevdalina Kandilarova, Vladimir Khorev, Semen Kurkin. Functional magnetic resonance imaging study of group independent components underpinning item responses to paranoid-depressive scaleWorld Journal of Clinical Cases 2023; 11(36): 8458-8474 doi: 10.12998/wjcc.v11.i36.8458
40
Yanyan Wei, Huanqin Gao, Yanhong Luo, Junhui Feng, Guoguang Li, Tingting Wang, Haiting Xu, Lu Yin, Jinbao Ma, Jingxu Chen. Systemic inflammation and oxidative stress markers in patients with unipolar and bipolar depression: A large-scale studyJournal of Affective Disorders 2024; 346 doi: 10.1016/j.jad.2023.10.156
41
Michael Maes, Décio Sabbatini Barbosa, Abbas F. Almulla, Buranee Kanchanatawan. A Novel Pathway Phenotype of Temporal Lobe Epilepsy and Comorbid Psychiatric Disorders: Results of Precision Nomothetic MedicineAntioxidants 2022; 11(5) doi: 10.3390/antiox11050803
42
Xing Luo, Jiangwen Dong, Tao Li. Comparative cytokine signatures and cognitive deficits in early-onset schizophrenia and adolescent major depression: Toward refined diagnostic classification frameworksJournal of Affective Disorders 2025; 389 doi: 10.1016/j.jad.2025.119667
43
Martina Nicole Modesti, Jan Francesco Arena, Antonio Del Casale, Giovanna Gentile, Marina Borro, Giovanna Parmigiani, Maurizio Simmaco, Cecilia Guariglia, Stefano Ferracuti. Lipidomics and genomics in mental health: insights into major depressive disorder, bipolar disorder, schizophrenia, and obsessive-compulsive disorderLipids in Health and Disease 2025; 24(1) doi: 10.1186/s12944-025-02512-x
44
Xuanyi Wang, Jie Shao, Pan Lin. Effective connectome-based predictive modeling reveals transdiagnostic heterogeneity of anhedonia from shared hubs to dissociable pathwaysBehavioural Brain Research 2026; 506 doi: 10.1016/j.bbr.2026.116135
45
Michael Maes, Laura Andrés-Rodríguez, Aristo Vojdani, Sunee Sirivichayakul, Decio S. Barbosa, Buranee Kanchanatawan. In Schizophrenia, Chronic Fatigue Syndrome- and Fibromyalgia-Like Symptoms are Driven by Breakdown of the Paracellular Pathway with Increased Zonulin and Immune Activation-Associated NeurotoxicityCNS & Neurological Disorders - Drug Targets 2023; 22(2) doi: 10.2174/1871527321666220806100600
46
Wenjia Liang, Lanwei Hou, Wenjun Wang, Bao Wang, Chenxi Sun, Yuan Zhang, Zhuoran Li, Rong Shi, Wenjuan Zhou, Yuchun Tang, Wei Wang, Lejin Yang, Shuwei Liu. Alterations in miR-151a-3p of plasma-derived exosomes and associated multimodal neuroimaging patterns in major depressive disorderMolecular Psychiatry 2025; 30(11) doi: 10.1038/s41380-025-03102-0
47
Michael HJ Maes, Drozdstoy Stoyanov. False dogmas in mood disorders research: Towards a nomothetic network approachWorld Journal of Psychiatry 2022; 12(5): 651-667 doi: 10.5498/wjp.v12.i5.651
48
Kristina Stoyanova, Drozdstoy Stoyanov, Vladimir Khorev, Semen Kurkin. Identifying neural network structures explained by personality traits: combining unsupervised and supervised machine learning techniques in translational validity assessmentThe European Physical Journal Special Topics 2025; 234(15) doi: 10.1140/epjs/s11734-024-01411-z
49
Marnie MacKay, Bohan H. Yang, Serdar M. Dursun, Glen B. Baker. The Gut-Brain Axis and the Microbiome in Anxiety Disorders, Post-Traumatic Stress Disorder and Obsessive-Compulsive DisorderCurrent Neuropharmacology 2024; 22(5) doi: 10.2174/1570159X21666230222092029
50
Chaichana Jaroonpipatkul, Jaruwan Onwanna, Chavit Tunvirachaisakul, Nutchawan Jittapiromsak, Yothin Rakvongthai, Aurauma Chutinet, Thitiporn Supasitthumrong, Michael Maes. Depressive symptoms due to stroke are strongly predicted by the volume and location of the cerebral infarction, white matter hyperintensities, hypertension, and age: A precision nomothetic psychiatry analysisJournal of Affective Disorders 2022; 309 doi: 10.1016/j.jad.2022.04.041
51
Michael Maes, Juliana Brum Moraes, Ana Congio, Heber Vargas, Sandra Nunes. Research and Diagnostic Algorithmic Rules (RADAR) for mood disorders, recurrence of illness, suicidal behaviours, and the patient’s lifetime trajectoryActa Neuropsychiatrica 2023; 35(2) doi: 10.1017/neu.2022.31
52
Jie Wang, Xiaodong Liu, Bess Yin-Hung Lam, Weicong Lu, Robin Shao, Xiaoyue Li, Runhua Wang, Fanyong Xu, Jinyong Chen, Aoling Cai, Benjamin Goldstein, Fei Du, Roger S McIntyre, Jinfeng Wu, Kangguang Lin. Genetic and neuroanatomical correlates of bipolar disorder in high-risk youthBMJ Mental Health 2026; 29(1) doi: 10.1136/bmjment-2025-302006
53
Michael Maes, Buranee Kanchanatawan. In (deficit) schizophrenia, a general cognitive decline partly mediates the effects of neuro-immune and neuro-oxidative toxicity on the symptomatome and quality of lifeCNS Spectrums 2021;  doi: 10.1017/S1092852921000419
54
Tangcong Chen, Mengqi Niu, Yueyang Luo, Jing Li, Abbas F. Almulla, Yingqian Zhang, Michael Maes. The acute phase inflammatory response as a key determinant of reduced lipid-associated antioxidant defenses in Chinese patients with major depressive disorderBrain, Behavior, and Immunity 2026; 138 doi: 10.1016/j.bbi.2026.106923
55
Giuseppe Marano, Emanuele Caroppo, Francesco Maria Lisci, Sara Rossi, Gianandrea Traversi, Osvaldo Mazza, Roberto Pola, Gabriele Sani, Eleonora Gaetani, Marianna Mazza. Neuromarkers in bipolar disorder: A narrative review bridging neuroscience and clinical practiceNeuroMarkers 2026; 3(2) doi: 10.1016/j.neumar.2025.100144
56
Milica M. Borovcanin. PsychoNeuroImmunologyIntegrated Science 2024; 30 doi: 10.1007/978-3-031-73061-0_17
57
Julian Gutzeit, Martin Weiß, Tierney Kuhn, Johanna Klinger-König, Fabian Streit, Christiane Jockwitz, Berit Brandes, Marvin N. Wright, Christoph M. Friedrich, Margarethe Woeckel, Rafael Mikolajczyk, Thomas Keil, Stefanie Castell, Philine Betker, Christopher L. Schlett, Till W. Bärnighausen, Fabian Bamberg, Matthias Günther, Jochen G. Hirsch, Tobias Pischon, Thoralf Niendorf, Michael F. Leitzmann, Patricia Bohmann, Kerstin Wirkner, Lilian Krist, Yanding Wang, Klaus Berger, Sebastian Walther, Hans J. Grabe, Jürgen Deckert, Svenja Caspers, Grit Hein, Angelika Erhardt-Lehmann. Multimodal phenotypic classification of generalized anxiety and panic using structural MRI data and psychosocial factors: machine learning results from the German National Cohort (NAKO) studyTranslational Psychiatry 2026; 16(1) doi: 10.1038/s41398-026-04131-1
58
Irina A. Mednova, Lyudmila A. Levchuk, Anastasiia S. Boiko, Olga V. Roschina, German G. Simutkin, Nikolay A. Bokhan, Anton J. M. Loonen, Svetlana A. Ivanova. Cytokine level in patients with mood disorder, alcohol use disorder and their comorbidityThe World Journal of Biological Psychiatry 2023; 24(3) doi: 10.1080/15622975.2022.2095439
59
Michael Maes, Walton Luiz Del Tedesco Junior, Marcell Alysson Batisti Lozovoy, Mayara Tiemi Enokida Mori, Tiago Danelli, Elaine Regina Delicato de Almeida, Alexandre Mestre Tejo, Zuleica Naomi Tano, Edna Maria Vissoci Reiche, Andréa Name Colado Simão. In COVID-19, NLRP3 inflammasome genetic variants are associated with critical disease and these effects are partly mediated by the sickness symptom complex: a nomothetic network approachMolecular Psychiatry 2022; 27(4) doi: 10.1038/s41380-021-01431-4
60
Hussein Kadhem Al-Hakeim, Hadi Hasan Hadi, Ghoufran Akeel Jawad, Michael Maes. Intersections between Copper, β-Arrestin-1, Calcium, FBXW7, CD17, Insulin Resistance and Atherogenicity Mediate Depression and Anxiety Due to Type 2 Diabetes Mellitus: A Nomothetic Network ApproachJournal of Personalized Medicine 2022; 12(1) doi: 10.3390/jpm12010023
61
Michael Maes, Muanpetch Rachayon, Ketsupar Jirakran, Pimpayao Sodsai, Siriwan Klinchanhom, Piotr Gałecki, Atapol Sughondhabirom, Agnieszka Basta-Kaim. The Immune Profile of Major Dysmood Disorder: Proof of Concept and Mechanism Using the Precision Nomothetic Psychiatry ApproachCells 2022; 11(7) doi: 10.3390/cells11071183
62
Diogo Telles Correia, Drozdstoy Stoyanov, Helio G. Rocha Neto. How to define today a medical disorder? Biological and psychosocial disadvantages as the paramount criteriaJournal of Evaluation in Clinical Practice 2022; 28(6) doi: 10.1111/jep.13592
63
Lizeth K. Pedraza, Rodrigo O. Sierra, Lucas de Oliveira Alvares. Systems consolidation and fear memory generalisation as a potential target for trauma-related disordersThe World Journal of Biological Psychiatry 2022; 23(9) doi: 10.1080/15622975.2022.2027010
64
Katie Pizzolato, David Thacker, Nicole Marie Del Toro-Pagán, Nishita S Amin, Abeer Hanna, Jacques Turgeon, Veronique Michaud. Utilizing Pharmacogenomics Results to Determine Opioid Appropriateness and Improve Pain Management in a Patient with OsteoarthritisPharmacogenomics and Personalized Medicine 2022;  doi: 10.2147/PGPM.S385272
65
Jin-Lei Wang, Xiang Li, Jia-Ru Fan, Jia-Ping Yan, Ze-Mao Gong, Yue Zhao, Dong-Mei Wang, Li Ma, Na Ma, Diao-Mei Guo, Lian-Sheng Ma. Integrity of the editing and publishing process is the basis for improving an academic journal’s Impact FactorWorld Journal of Gastroenterology 2022; 28(43): 6168-6202 doi: 10.3748/wjg.v28.i43.6168