Mycosis fungoides: A mimicker of benign dermatoses

Figure 1 Mycosis fungoides presenting with annular lesions. Clinical photographs of an 80-year-old male patient (case 1) with slowly progressive annular, cockadiform and arcuate lesions resembling tinea corporis (A), erythema exsudativum multiforme (B), and granuloma annulare (C), respectively.

Figure 2 Mycosis fungoides resembling rosaea and Sézary-syndrome mimicking Ofuji´s papuloerythroderma. A: Clinical images of a 46-year-old patient with granulomatous mycosis fungoides imitating rosacea and at the same time exhibiting clinical features of dermal elastolysis due to granulomatous slack skin syndrome (B) (case 9); C and D: Clinical images of a 71-year old patient with mycosis fungoides/Sézary-syndrome masquerading as Ofuji´s papuloerythroderma (case 2).

Figure 3 Mycosis fungoides as imitator of benign inflammatory dermatoses. Clinical photomicrographs of skin lesions of mycosis fungoides mimicking urticaria pigmentosa (A) (case 5), plantar eczema (B) (case 7) and vitiligo/pityriasis alba (C) (case 6).

Figure 4 Histological findings. A: Case 5 exhibitis extensive purpuric changes, pigment incontinence, interface dermatitis (HE staining, magnification 400 ×. Inlet iron staining); B: CD8⁺ cytotoxic epidermotropic infiltrate is depicted (CD8 immunohistochemical staining).

Figure 5 Schematic diagnostic algorithms for the clinical and histopathological work-up of “mimicking” cases of mycosis fungoides.