Antibiotic-loaded phosphatidylcholine inhibits staphylococcal bone infection

Figure 1 Representative radiographs from implant-associated osteomyelitis model after 7 d in antibiotic-coated group (top) and uncoated control group (bottom). Location of Ti wires and swelling in tissue surrounding implants are noted by arrows.

Figure 2 Graphical representation of bacteriological scores from surrounding tissue on a 0-4 point scale. Data is represented as mean ± SD. Statistically significant difference between groups was determined by Mann-Whitney Rank Sum test (^aP < 0.05).

Figure 3 Graphical representation of log colony forming units retrieved from Ti wires. Data is represented as mean ± SD. Statistically significant difference between groups was determined by Mann-Whitney Rank Sum test (^aP < 0.05). CFUs: Colony forming units.

Figure 4 Plot of histological scores for uncoated and coated groups. Statistically significant difference between groups was determined by Mann-Whitney Rank Sum test (^aP < 0.05).

Figure 5 Photomicrographs of sections of decalcified bone stained with hematoxylin and eosin and the modified Gram stain at 4 × and 10 ×. Approximate areas of higher magnification are denoted by blue boxes. Areas where pin was removed and areas of visible staphylococci are marked with arrows.