Role of neutrophil to lymphocyte ratio in osteoarthritis: A systematic review and meta-analysis

Figure 1 PRISMA Flow diagram for new systematic reviews, which includes searches of databases, registers, and other sources. NLR: Neutrophil-to-lymphocyte ratio.

Figure 2 Meta-analysis of neutrophil-to-lymphocyte ratio levels. A: Meta-analysis of neutrophil-to-lymphocyte ratio (NLR) levels in patients with osteoarthritis (OA) compared to healthy controls; B: Subgroup meta-analysis of NLR levels in patients with OA compared to healthy controls, according to study design; C: Meta-analysis of NLR levels in patients with severe OA compared to those with mild-moderate OA; D: Funnel plot showing publication bias. Studies on NLR levels in patients with OA compared to healthy controls; E: Studies on NLR levels in patients with severe OA compared to those with mild-moderate OA. SMD: Standardized mean difference; CI: Confidence interval.