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©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. Jul 18, 2014; 5(3): 312-318
Published online Jul 18, 2014. doi: 10.5312/wjo.v5.i3.312
Published online Jul 18, 2014. doi: 10.5312/wjo.v5.i3.312
Rheumatoid arthritis: Nuclear Medicine state-of-the-art imaging
Paulo Henrique Rosado-de-Castro, Sergio Augusto Lopes de Souza, Lea Mirian Barbosa da Fonseca, Bianca Gutfilen, Departamento de Radiologia, Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-913, Brazil
Dângelo Alexandre, Instituto Nacional de Traumatologia e Ortopedia, Rio de Janeiro 20940-070, Brazil
Author contributions: Rosado-de-Castro PH, Lopes de Souza SA, Alexandre D, Barbosa da Fonseca LM and Gutfilen B performed the literature review, drafted the article, revised the article critically for important intellectual content and finally approved for print.
Correspondence to: Bianca Gutfilen, PhD, Professor, Departamento de Radiologia, Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Ilha do Fundão, Rio de Janeiro 21941-913, Brazil. bianca.gutfilen@gmail.com
Telephone: +55-21-25622399 Fax: +55-21-25622399
Received: December 27, 2013
Revised: April 4, 2014
Accepted: April 25, 2014
Published online: July 18, 2014
Revised: April 4, 2014
Accepted: April 25, 2014
Published online: July 18, 2014
Core Tip
Core tip: In recent years, the use of nuclear medicine to characterize and diagnose infectious and inflammatory diseases has been rapidly increasing. In the case of rheumatoid arthritis (RA), the success of treatment requires improvement of early diagnosis and assessment of response to anti-inflammatory therapy. In this setting, Nuclear Medicine may be valuable in the assessment of early inflammatory activity in RA, foreseeing and monitoring response to treatment, and allowing the selection of optimal treatments for each patient. The development of new radiopharmaceuticals and hybrid imaging technologies may improve the potential of molecular imaging in the field.