Factors predicting upstaging from clinical N0 to pN2a/N3a in breast cancer patients
Goshi Oda, Tsuyoshi Nakagawa, Department of Breast Surgery, Tokyo Medical and Dental University, Tokyo 1138519, Japan
Hiroki Mori, Department of Plastic and Reconstructive Surgery, Tokyo Medical and Dental University, Tokyo 1138519, Japan
Iichiro Onishi, Department of Pathology, Tokyo Medical and Dental University, Tokyo 1138519, Japan
Tomoyuki Fujioka, Mio Mori, Kazunori Kubota, Department of Radiology, Tokyo Medical and Dental University, Tokyo 1138519, Japan
Ryoichi Hanazawa, Akihiro Hirakawa, Department of Clinical Biostatistics, Tokyo Medical and Dental University, Tokyo 1138519, Japan
Toshiaki Ishikawa, Kentaro Okamoto, Hiroyuki Uetakesszsz, Department of Specialized Surgeries, Tokyo Medical and Dental University, Tokyo 1138519, Japan
Author contributions: Oda G contributed to the conceptualization, methodology, software, validation, formal analysis, visualization and writing-original draft preparation; Hanazawa R, Hirakawa A contributed to the statistical checks; Oda G, Nakagawa T, Mori H, Onishi I, Fujioka T, Mori M, and Kubota K contributed to the investigation, resources; Oda G and Mori M contributed to the data curation; Nakagawa T contributed to the writing-review and editing; Okamoto K, Ishikawa T and Uetakesszsz H contributed to the supervision; All authors have read and agreed to the published version of the manuscript.
Institutional review board statement: The study was conducted according to the guidelines of the Declaration of Helsinki, and approved by the Ethics Committee of Tokyo Medical and Dental University, Tokyo, Japan (M2019-137, date of approval: 19 September 2019).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare no conflict of interest.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at firstname.lastname@example.org.
STROBE statement: The authors have read the STROBE Statement checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Goshi Oda, MD, PhD, Assistant Lecturer, Doctor, Department of Breast Surgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 1138519, Japan. email@example.com
Received: May 25, 2022
Peer-review started: May 25, 2022
First decision: July 13, 2022
Revised: July 25, 2022
Accepted: September 6, 2022
Article in press: September 6, 2022
Published online: September 24, 2022