Low dose oral curcumin is not effective in induction of remission in mild to moderate ulcerative colitis: Results from a randomized double blind placebo controlled trial
Saurabh Kedia, Sushil Garg, Venigalla Pratap Mouli, Sawan Bopanna, Veena Tiwari, Govind Makharia, Vineet Ahuja, Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi 110029, India
Vikram Bhatia, Department of Gastroenterology, Institute of Liver and Biliary Sciences, New Delhi 110070, India
Sandeep Thareja, Department of Gastroenterology, Army Hospital - Research and Referral, New Delhi 110070, India
Author contributions: Ahuja V planned and conducted the study, collecting and interpreting data; Kedia S and Ahuja V drafted the manuscript; Garg S analyzed data; Kedia S, Bhatia V, Thareja S, Mouli VP, Bopanna S, Tiwari V and Makharia G critically revised the manuscript for important intellectual content and final approval of the manuscript; all authors have approved the final draft submitted.
Institutional review board statement: The study was reviewed and approved institute ethics committee at All India Institute of Medical Sciences, New Delhi.
Informed consent statement: All study participants provided informed written consent prior to study enrollment.
Clinical trial registration statement: This trial was done from 2003 till 2005. Since there was no trial registry in India at that time, this trial did not have a registration number.
Conflict-of-interest statement: No conflict of interest for all authors.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Vineet Ahuja, Professor, Department of Gastroenterology, All India Institute of Medical Sciences, Room No. 3093, Third Floor, Teaching Block, AIIMS, New Delhi 110029, India. firstname.lastname@example.org
Telephone: +91-11-26593300 Fax: +91-11-26588663
Received: October 17, 2016
Peer-review started: October 19, 2016
First decision: December 27, 2016
Revised: January 5, 2017
Accepted: March 12, 2017
Article in press: March 14, 2017
Published online: May 6, 2017