Vivas S, Vaquero L, Rodríguez-Martín L, Caminero A. Age-related differences in celiac disease: Specific characteristics of adult presentation. World J Gastrointest Pharmacol Ther 2015; 6(4): 207-212 [PMID: 26558154 DOI: 10.4292/wjgpt.v6.i4.207]
Corresponding Author of This Article
Santiago Vivas, MD, Department of Gastroenterology, University Hospital of León, Altos de Nava s/n, 24008 León, Spain. svivasa@gmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Pharmacol Ther. Nov 6, 2015; 6(4): 207-212 Published online Nov 6, 2015. doi: 10.4292/wjgpt.v6.i4.207
Age-related differences in celiac disease: Specific characteristics of adult presentation
Santiago Vivas, Luis Vaquero, Laura Rodríguez-Martín, Alberto Caminero
Santiago Vivas, Institute of Biomedicine (IBIOMED), University of León, 24008 León, Spain
Santiago Vivas, Luis Vaquero, Laura Rodríguez-Martín, Department of Gastroenterology, University Hospital of León, 24008 Léon, Spain
Alberto Caminero, Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, Ontario L8S 4K1, Canada
Author contributions: Vaquero L and Rodríguez-Martín L wrote the paper, and prepared the figures and tables; Vivas S and Caminero A designed the outline and coordinated the writing of the paper.
Conflict-of-interest statement: The authors declare that there are no conflicts of interest regarding the publication of this paper.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Santiago Vivas, MD, Department of Gastroenterology, University Hospital of León, Altos de Nava s/n, 24008 León, Spain. svivasa@gmail.com
Received: June 2, 2015 Peer-review started: June 3, 2015 First decision: August 4, 2015 Revised: August 24, 2015 Accepted: October 12, 2015 Article in press: October 13, 2015 Published online: November 6, 2015
Abstract
Celiac disease may appear both in early childhood and in elderly subjects. Current knowledge of the disease has revealed some differences associated to the age of presentation. Furthermore, monitoring and prognosis of celiac subjects can vary depending on the pediatric or adult stage. The main objective of this review is to provide guidance for the adult diagnostic and follow-up processes, which must be tailored specifically for adults and be different from pediatric patients.
Core tip: Current knowledge of celiac disease (CD) has revealed differences linked to the age of onset. These differences are related to the epidemiology, pathogenicity, clinical signs and prognosis of the disease. Here we present a comprehensive review of CD focusing on the age-specific management of patients. The knowledge of particular aspects linked to either adults or children would improve both the diagnosis and follow-up of this disease. This review can be helpful to the clinician involved in the management of adult and pediatric patients.
