Published online Nov 6, 2015. doi: 10.4292/wjgpt.v6.i4.207
Peer-review started: June 3, 2015
First decision: August 4, 2015
Revised: August 24, 2015
Accepted: October 12, 2015
Article in press: October 13, 2015
Published online: November 6, 2015
Celiac disease may appear both in early childhood and in elderly subjects. Current knowledge of the disease has revealed some differences associated to the age of presentation. Furthermore, monitoring and prognosis of celiac subjects can vary depending on the pediatric or adult stage. The main objective of this review is to provide guidance for the adult diagnostic and follow-up processes, which must be tailored specifically for adults and be different from pediatric patients.
Core tip: Current knowledge of celiac disease (CD) has revealed differences linked to the age of onset. These differences are related to the epidemiology, pathogenicity, clinical signs and prognosis of the disease. Here we present a comprehensive review of CD focusing on the age-specific management of patients. The knowledge of particular aspects linked to either adults or children would improve both the diagnosis and follow-up of this disease. This review can be helpful to the clinician involved in the management of adult and pediatric patients.