Genetic update on inflammatory factors in ulcerative colitis: Review of the current literature

doi:10.4291/wjgp.v5.i3.304

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 5, Issue 3

This Article

Academic Content and Language Evaluation of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (6061)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-1) series.

Item

Count

PDF

440

WORD

322

HTML

4376

Figures (1-1)

143

Sum=5281

Aug 15, 2014 (publication date) through Apr 26, 2024

Times Cited of This Article

Times Cited (24)

Journal Information of This Article

Publication Name

World Journal of Gastrointestinal Pathophysiology

ISSN

2150-5330

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Review

World J Gastrointest Pathophysiol. Aug 15, 2014; 5(3): 304-321
Published online Aug 15, 2014. doi: 10.4291/wjgp.v5.i3.304

Genetic update on inflammatory factors in ulcerative colitis: Review of the current literature

Patricia Sarlos, Erzsebet Kovesdi, Lili Magyari, Zsolt Banfai, Andras Szabo, Andras Javorhazy, Bela Melegh

Patricia Sarlos, 1^st Department of Internal Medicine, University of Pecs, 7623 Pecs, Hungary

Erzsebet Kovesdi, Lili Magyari, Zsolt Banfai, Andras Szabo, Bela Melegh, Department of Medical Genetics, University of Pecs, 7624 Pecs, Hungary

Erzsebet Kovesdi, Lili Magyari, Zsolt Banfai, Andras Szabo, Bela Melegh, Szentagothai Research Centre, 7624 Pecs, Hungary

Andras Javorhazy, Department of Urology, University of Pecs, 7621 Pecs, Hungary

Author contributions: Sarlos P, Kovesdi E, Magyari L, Banfai Z, Szabo A, Javorhazy A, Melegh B contributed equally to this work; Melegh B conceived the study; Kovesdi E, Magyari L, Banfai Z wrote the genetic part of the study; Sarlos P, Szabo A wrote the clinical section of the review; Javorhazy A prepared the Figure.

Supported by The grant of the Hungarian Science Foundation, No. OTKA K103983

Correspondence to: Bela Melegh, MD, PhD, DSc, Department of Medical Genetics, University of Pecs, Szigeti 12, 7624 Pecs, Hungary. bela.melegh@aok.pte.hu

Telephone: +36-72-536427 Fax: +36-72-536032

Received: January 28, 2014
Revised: March 19, 2014
Accepted: July 12, 2014
Published online: August 15, 2014

Core Tip

Core tip: Ulcerative colitis (UC) is a disorder of the idiopathic and chronic inflammation of the colonic mucosa. Several genetics factors influence the development of the disease, especially interleukin and interleukin receptor gene polymorphisms and other inflammation-related genes. In this review we collected the current literature on PubMed Database about those genetic markers that are associated with UC, we focused on the following terminology: UC, inflammation, genes, polymorphisms, susceptibility.