Published online Nov 28, 2014. doi: 10.4329/wjr.v6.i11.855
Revised: September 3, 2014
Accepted: September 23, 2014
Published online: November 28, 2014
Core tip: Each voxel in a brain magnetic resonance imaging (MRI) may contain multiple types of tissue. Partial volume estimation refers to a generalized image segmentation task where the amount of each tissue type within each image voxel of brain MRI is solved. This is important for volume quantification and cortical thickness analysis due to the geometrical complexity of human brain structure. This review aims to provide a systematic, tutorial-like overview of methods for partial volume estimation in brain MRI.