Published online Nov 28, 2014. doi: 10.4329/wjr.v6.i11.850
Revised: June 16, 2014
Accepted: September 23, 2014
Published online: November 28, 2014
Core tip: The Macklin effect can be frequently seen on imaging by multidetector-row computed tomography (CT) of patients who are found to have spontaneous pneumomediastinum from respiratory causes other than chest trauma. The collections of air dissect along the bronchovascular sheaths to the hilum and into the mediastinum. The Macklin effect as seen on CT may help differentiate respiratory from other etiologies of pneumomediastinum.