Chika CE. Advances in dual energy computed tomography approach for proton stopping power ratio computation in radiotherapy. World J Radiol 2025; 17(6): 105728 [DOI: 10.4329/wjr.v17.i6.105728]
Corresponding Author of This Article
Charles Ekene Chika, PhD, Department of Mathematics, University of Nigeria, Obukpa Road, Nsukka 410001, Nigeria. charles.chika@unn.edu.ng
Research Domain of This Article
Radiology, Nuclear Medicine & Medical Imaging
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Radiol. Jun 28, 2025; 17(6): 105728 Published online Jun 28, 2025. doi: 10.4329/wjr.v17.i6.105728
Advances in dual energy computed tomography approach for proton stopping power ratio computation in radiotherapy
Charles Ekene Chika
Charles Ekene Chika, Department of Mathematics, University of Nigeria, Nsukka 410001, Nigeria
Author contributions: Chika CE conceptualized and wrote the manuscript as well as completed all the research and manuscript process.
Conflict-of-interest statement: The author reports no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Charles Ekene Chika, PhD, Department of Mathematics, University of Nigeria, Obukpa Road, Nsukka 410001, Nigeria. charles.chika@unn.edu.ng
Received: February 5, 2025 Revised: March 14, 2025 Accepted: May 24, 2025 Published online: June 28, 2025 Processing time: 141 Days and 20.4 Hours
Abstract
To address the sensitive and uncertain limitations of single-energy computed tomography (CT) calibration methods in computing proton stopping power ratio during treatment planning, different methods have been proposed using a dual energy CT approach. This paper reviews the most recent dual-energy CT approaches for computing proton stopping power ratio. These include image domain and projection domain methods. The advantages and uncertainties of these methods are analyzed based on existing studies. This paper highlights recent advances in dual energy CT, discussing their implementation, advantages, limitations, and potential for clinical adoption.
Core Tip: This literature presents different methods of calculating proton stopping power ratio using dual energy computed tomography data. It outlines the implementation of different algorithms, review different research works and propose further research works that need to be carried out to facilitate the clinical implementation of dual energy computed tomography approach to improve ion therapy.
