Editorial
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Jun 27, 2025; 17(6): 104883
Published online Jun 27, 2025. doi: 10.4240/wjgs.v17.i6.104883
Systemic complications and management strategies in liver cancer patients undergoing interventional therapy
Yue-Zhan Shan, Yan Jiao, Hui-Ling Guo, Ya-Hui Liu
Yue-Zhan Shan, Hui-Ling Guo, Department of Gastrointestinal Colorectal Surgery, China-Japan Union Hospital of Jilin University, Changchun 130022, Jilin Province, China
Yan Jiao, Ya-Hui Liu, Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China
Co-corresponding authors: Hui-Ling Guo and Ya-Hui Liu.
Author contributions: Guo HL designed the overall concept and outline of the manuscript; Shan YZ contributed to the discussion and design of the manuscript; Jiao Y and Liu YH contributed to the writing and editing of the manuscript, illustrations, and review of the literature; Guo HL and Liu YH contributed equally as co-corresponding authors.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ya-Hui Liu, Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, Xinmin Street, Changchun 130021, Jilin Province, China. yahui@jlu.edu.cn
Received: January 5, 2025
Revised: February 23, 2025
Accepted: March 11, 2025
Published online: June 27, 2025
Processing time: 145 Days and 20.5 Hours
Core Tip

Core Tip: Liver cancer management demands a comprehensive approach to address systemic complications arising from interventional and systemic therapies. These complications, spanning cardiovascular, renal, hematological, and metabolic domains, significantly affect patient outcomes and quality of life. Advances in interventional techniques, combination therapies, and supportive technologies such as artificial intelligence provide innovative solutions for optimizing care. Multidisciplinary collaboration remains pivotal in tailoring interventions to individual patient needs. Future research should emphasize refining therapeutic strategies, improving patient selection, and leveraging biomarkers for early detection to ensure holistic and effective management of liver cancer.