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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Aug 15, 2025; 16(8): 106967
Published online Aug 15, 2025. doi: 10.4239/wjd.v16.i8.106967
Published online Aug 15, 2025. doi: 10.4239/wjd.v16.i8.106967
Performance of flash continuous glucose monitoring and glycemic marker correlations in Chinese pregnant women with non-type 1 diabetes
Ling Lyu, Yi-Ling Huang, Yu Huang, Ze-Yu Wu, Fan Ping, Yu-Xiu Li, Department of Endo
Co-corresponding authors: Fan Ping and Yu-Xiu Li.
Author contributions: Lyu L performed formal analysis, visualization, and wrote the original draft; Huang YL conducted the investigation; Huang YL, Huang Y, Wu ZY, Ping F, and Li YX participated in the review and editing of the manuscript; Lyu L and Wu ZY performed data curation; Huang Y supervised the study; Ping F and Li YX conceptualized the study, developed the methodology, acquired funding, they contributed equally to this article, they are the co-corresponding authors of this manuscript; and all authors thoroughly reviewed and endorsed the final manuscript.
Supported by the National High Level Hospital Clinical Research Funding, No. 2022-PUMCH-B-015; and the Healthcare Quality and Safety Incubation Program of Peking Union Medical Foundation, No. XHFY2406.
Institutional review board statement: This study was approved by the Medical Ethics Committee of Peking Union Medical College Hospital, approval No. I-24PJ2607.
Informed consent statement: All study participants, or their legal guardians, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: Technical appendix, statistical code, and dataset are available from the corresponding author at pingfan@pumch.cn. Participants gave informed consent for data sharing.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Fan Ping, MD, Associate Professor, Department of Endocrinology, Key Laboratory of Endocrinology, Ministry of Health, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, No. 1 Shuai-Fu-Yuan Street, Dongcheng District, Beijing 100730, China. pingfan@pumch.cn
Received: March 12, 2025
Revised: May 14, 2025
Accepted: June 30, 2025
Published online: August 15, 2025
Processing time: 155 Days and 21.7 Hours
Revised: May 14, 2025
Accepted: June 30, 2025
Published online: August 15, 2025
Processing time: 155 Days and 21.7 Hours
Core Tip
Core Tip: This study demonstrates the reliability of the FreeStyle Libre H flash continuous glucose monitoring (FCGM) system in pregnant women with gestational diabetes mellitus and type 2 diabetes mellitus, showing a low mean absolute relative difference of 7.96% compared to venous plasma glucose. Hemoglobin A1c (HbA1c) and glycated albumin (GA) showed significant linear or non-linear associations with FCGM metrics, although both were influenced by gestational age and pregestational body mass index. In this study, FCGM served as a validated reference for evaluating HbA1c and GA. HbA1c remained a reliable marker, while GA provided supplementary value for comprehensive glycemic assessment.