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©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Mar 15, 2019; 10(3): 169-180
Published online Mar 15, 2019. doi: 10.4239/wjd.v10.i3.169
Published online Mar 15, 2019. doi: 10.4239/wjd.v10.i3.169
Antidiabetic treatment on memory and spatial learning: From the pancreas to the neuron
Eleni Xourgia, Athanasia Papazafiropoulou, Andreas Melidonis 1st Department of Internal Medicine and Diabetes Center, Tzaneio General Hospital of Piraeus, Athens 18536, Greece
Author contributions: All authors equally contributed to this paper with conception and design of the study, literature review and analysis, drafting and critical revision and editing, and final approval of the final version.
Conflict-of-interest statement: No potential conflicts of interest. No financial support.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Athanasia Papazafiropoulou, MD, MSc, PhD, Attending Doctor, Research Scientist, 1st Department of Internal Medicine and Diabetes Center, Tzaneio General Hospital of Piraeus, 1 Zanni and Afentouli Street, Athens 18536, Greece. pathan@ath.forthnet.gr
Telephone: +30-697-996483
Received: February 20, 2019
Peer-review started: February 20, 2019
First decision: February 26, 2019
Revised: March 1, 2019
Accepted: March 8, 2019
Article in press: March 8, 2019
Published online: March 15, 2019
Peer-review started: February 20, 2019
First decision: February 26, 2019
Revised: March 1, 2019
Accepted: March 8, 2019
Article in press: March 8, 2019
Published online: March 15, 2019
Core Tip
Core tip: In this review, we aim to create a concise overview of the effects exerted by hyperglycemia on neural tissue, while describing the potential of each antidiabetic drug to improve functional and cognitive capacity in subjects with diabetic encephalopathy.