Systematic Reviews
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Feb 15, 2019; 10(2): 96-113
Published online Feb 15, 2019. doi: 10.4239/wjd.v10.i2.96
Effectiveness of royal jelly supplementation in glycemic regulation: A systematic review
Kamel Omer, Maxwell J Gelkopf, Genevieve Newton
Kamel Omer, Maxwell J Gelkopf, Genevieve Newton, Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada
Author contributions: Omer K and Newton G conceptualized research question and created search strategy; Omer K and Gelkopf MJ conducted full text inclusions and risk of bias assessments; Omer K and Newton G conducted GRADE assessment; Newton G reviewed manuscript throughout writing stage; Omer K conducted database search, data extraction and analysis, and manuscript preparation.
Conflict-of-interest statement: The authors declare no conflict of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 checklist.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Genevieve Newton, BSc, MSc, PhD, Associate Professor, Human Health and Nutritional Sciences, University of Guelph, 50 Stone Road East, Guelph, ON N1G2W1, Canada.
Telephone: +1-519-8244120-56822 Fax: +1-519-7635902
Received: November 15, 2018
Peer-review started: November 15, 2018
First decision: November 29, 2018
Revised: January 29, 2019
Accepted: February 11, 2019
Article in press: February 12, 2019
Published online: February 15, 2019
Core Tip

Core tip: Royal jelly (RJ) is a promising natural treatment to improve high blood glucose. Insulin sensitivity, fasting blood glucose levels, and rate of glucose clearance are among the glycemic parameters investigated in the current systematic review that are shown to approach normal levels due to regular RJ intake.