Published online Sep 15, 2023. doi: 10.4239/wjd.v14.i9.1403
Peer-review started: June 6, 2023
First decision: June 21, 2023
Revised: June 30, 2023
Accepted: July 18, 2023
Article in press: July 18, 2023
Published online: September 15, 2023
Urinary sepsis is frequently seen in patients with diabetes mellitus (DM) complicated with upper urinary tract calculi (UUTCs). Currently, the known risk factors of urinary sepsis are not uniform.
To analyze the risk factors of concurrent urinary sepsis in patients with DM complicated with UUTCs by logistic regression.
We retrospectively analyzed 384 patients with DM complicated with UUTCs treated in People’s Hospital of Jincheng between February 2018 and May 2022. The patients were screened according to the inclusion and exclusion criteria, and 204 patients were enrolled. The patients were assigned to an occurrence group (n = 78) and a nonoccurrence group (n = 126). Logistic regression was adopted to analyze the risk factors for urinary sepsis, and a risk prediction model was established.
Gender, age, history of lumbago and abdominal pain, operation time, urine leukocytes (U-LEU) and urine glucose (U-GLU) were independent risk factors for patients with concurrent urinary sepsis (P < 0.05). Risk score = 0.794 × gender + 0.941 × age + 0.901 × history of lumbago and abdominal pain - 1.071 × operation time + 1.972 × U-LEU + 1.541 × U-GLU. The occurrence group had notably higher risk scores than the nonoccurrence group (P < 0.0001). The area under the curve of risk score for forecasting concurrent urinary sepsis in patients was 0.801, with specificity of 73.07%, sensitivity of 79.36% and Youden index of 52.44%.
Sex, age, history of lumbar and abdominal pain, operation time, ULEU and UGLU are independent risk factors for urogenic sepsis in diabetic patients with UUTC.
Core Tip: This study was to determine risk factors of concurrent urinary sepsis in patients with diabetes mellitus comorbid with upper urinary tract calculi and construct a risk prediction model. Gender, age, history of lumbago and abdominal pain, operation time, urinary leukocytes and urinary glucose were independent risk factors for concurrent urinary sepsis. It is helpful to identify high-risk patients at an early stage and implement active and effective intervention measures to reduce complications and improve the prognosis of patients.