Associations between serum biomarkers and gut microbial imbalance in predicting chemotherapy response in colorectal cancer: A retrospective analysis

doi:10.4251/wjgo.v17.i8.108870

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Aug 15, 2025 (publication date) through Aug 14, 2025

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

World J Gastrointest Oncol. Aug 15, 2025; 17(8): 108870
Published online Aug 15, 2025. doi: 10.4251/wjgo.v17.i8.108870

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Figure 1 Serum S100A12 and soluble CD14 Levels in colorectal cancer patients stratified by gut microbiota composition. Compared with the normal microbiota group, ^aP < 0.05; compared with the grade I dysbiosis group, ^bP < 0.05. sCD14: Soluble CD14.

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Figure 2 Receiver operating characteristic curve analysis of S100A12 and soluble CD14 in predicting chemotherapy non-response. sCD14: Soluble CD14.

Citation: Ling MZ, Wan Z, Hu B, Zhao MJ, Gong HS, Li G. Associations between serum biomarkers and gut microbial imbalance in predicting chemotherapy response in colorectal cancer: A retrospective analysis. World J Gastrointest Oncol 2025; 17(8): 108870
URL: https://www.wjgnet.com/1948-5204/full/v17/i8/108870.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i8.108870