Associations between serum biomarkers and gut microbial imbalance in predicting chemotherapy response in colorectal cancer: A retrospective analysis

doi:10.4251/wjgo.v17.i8.108870

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 17, Issue 8

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (0)

All Articles published online

The chart showing PDF series, HTML series, Figures (1-2) series, Tables (1-5) series.

Item

Count

PDF

HTML

Figures (1-2)

Tables (1-5)

Sum=0

Aug 15, 2025 (publication date) through Aug 14, 2025

Times Cited of This Article

Times Cited (0)

Journal Information of This Article

Publication Name

World Journal of Gastrointestinal Oncology

ISSN

1948-5204

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

World J Gastrointest Oncol. Aug 15, 2025; 17(8): 108870
Published online Aug 15, 2025. doi: 10.4251/wjgo.v17.i8.108870

Associations between serum biomarkers and gut microbial imbalance in predicting chemotherapy response in colorectal cancer: A retrospective analysis

Ming-Zhi Ling, Zhen Wan, Biao Hu, Ming-Jing Zhao, Hao-Sheng Gong, Gang Li

Ming-Zhi Ling, Zhen Wan, Biao Hu, Ming-Jing Zhao, Hao-Sheng Gong, Gang Li, Department of Laboratory Medicine, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou 450003, Henan Province, China

Author contributions: Ling MZ and Li G designed the study; Wan Z and Hu B performed the experiments; Zhao MJ and Gong HS analyzed the data; all authors contributed to editorial changes in the manuscript, read and approved the final manuscript.

Institutional review board statement: This study was approved by the Medical Ethics Committee of Henan Provincial People's Hospital, and the study followed the ethical guidelines of the Declaration of Helsinki.

Informed consent statement: Informed consent was obtained from all study participants.

Conflict-of-interest statement: The authors declare that they have no competing interests.

Data sharing statement: No additional data are available.

Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Gang Li, PhD, Associate Chief Physician, Department of Laboratory Medicine, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, No. 7 Weiwu Road, Zhengzhou 450003, Henan Province, China. ligang65580@126.com

Received: May 14, 2025
Revised: June 8, 2025
Accepted: July 15, 2025
Published online: August 15, 2025
Processing time: 91 Days and 15.9 Hours

Core Tip

Core Tip: This study highlights the potential of S100A12 and soluble CD14 as non-invasive biomarkers for assessing gut microbial imbalance and predicting chemotherapy responsiveness in colorectal cancer. Their integration into clinical decision-making could support more personalized and effective treatment planning.