Significance of serum APE1-AAbs, PTX-3, and miR-486-3p in patients with colorectal cancer undergoing radical surgery

doi:10.4251/wjgo.v17.i5.105192

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May 15, 2025 (publication date) through May 15, 2025

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. May 15, 2025; 17(5): 105192
Published online May 15, 2025. doi: 10.4251/wjgo.v17.i5.105192

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Figure 1 Comparison of apurinic/apyrimidinic endonuclease 1 autoantibodies, peripheral pentraxin-3, and miR-486-3p Levels. ^aP < 0.05 vs occurrence group. APE1-AAbs: Apurinic/apyrimidinic endonuclease 1 autoantibodies; PTX-3: Peripheral pentraxin-3.

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Figure 2 Relationship of apurinic/apyrimidinic endonuclease 1 autoantibodies, peripheral pentraxin-3, and miR-486-3p levels with postoperative recurrence and metastasis of colorectal cancer. APE1-AAbs: Apurinic/apyrimidinic endonuclease 1 autoantibodies; PTX-3: Peripheral pentraxin-3; CRC: Colorectal cancer.

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Figure 3 Receiver operating characteristic curves of apurinic/apyrimidinic endonuclease 1 autoantibodies, peripheral pentraxin-3, and miR-486-3p levels alone and their combination for predicting postoperative recurrence and metastasis of colorectal cancer. APE1-AAbs: Apurinic/apyrimidinic endonuclease 1 autoantibodies; PTX-3: Peripheral pentraxin-3.

Citation: Wang H, Wang W. Significance of serum APE1-AAbs, PTX-3, and miR-486-3p in patients with colorectal cancer undergoing radical surgery. World J Gastrointest Oncol 2025; 17(5): 105192
URL: https://www.wjgnet.com/1948-5204/full/v17/i5/105192.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i5.105192