Gender differences in the relationship between alcohol consumption and gastric cancer risk are uncertain and not well-delineated

doi:10.4251/wjgo.v13.i12.2216

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Dec 15, 2021 (publication date) through Apr 25, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Letter to the Editor

World J Gastrointest Oncol. Dec 15, 2021; 13(12): 2216-2218
Published online Dec 15, 2021. doi: 10.4251/wjgo.v13.i12.2216

Gender differences in the relationship between alcohol consumption and gastric cancer risk are uncertain and not well-delineated

Henu Kumar Verma, LVKS Bhaskar

Henu Kumar Verma, Department of Immunopathology, Institute of lungs Biology and Disease, Comprehensive Pneumology Center, Helmholtz Zentrum, Neuherberg 85764, Munich, Germany

LVKS Bhaskar, Department of Zoology, Guru Ghasidas Vishwavidyalaya, Bilaspur 495001, Chhattisgarh, India

Author contributions: Verma HK and Bhaskar LVKS both the author wrote and revised the letter.

Conflict-of-interest statement: The authors declare no conﬂict of interest.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Henu Kumar Verma, PhD, Research Scientist, Department of Immunopathology, Institute of lungs Biology and Disease, Comprehensive Pneumology Center, Helmholtz Zentrum, Ingolstädter Landstrasse 1, Neuherberg 85764, Munich, Germany. henu.verma@yahoo.com

Received: May 11, 2021
Peer-review started: May 11, 2021
First decision: June 16, 2021
Revised: June 17, 2021
Accepted: November 3, 2021
Article in press: November 3, 2021
Published online: December 15, 2021

Abstract

The role of alcoholic and other beverage consumption in the etiology of gastric cancer is unknown. Several studies have summarized and established a significant association between heavy alcohol consumption and gastric cancer risk, but evidence on alcohol-related cancer risk is conflicting.

Keywords: Alcohol, Gastric cancer, Meta-analysis, Gender and alcohol intake, Alcohol consumption

Core Tip: Alcohol consumption among adult men and women is consistently linked to an increased risk of gastric cancer. Its role as a confounding factor in the gastric cancer burden is frequently overlooked. Although many cancers are genetically determined, most cancers are caused by interactions between the host and environmental/lifestyle factors.