Letter to the Editor
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. May 16, 2025; 17(5): 107183
Published online May 16, 2025. doi: 10.4253/wjge.v17.i5.107183
Advancement of haemostatic self-assembling peptides in the treatment of gastrointestinal bleeding: What role for PuraStat®?
Raffaele Pellegrino, Antonietta Gerarda Gravina
Raffaele Pellegrino, Antonietta Gerarda Gravina, Division of Hepatogastroenterology, Department of Precision Medicine, University of Campania Luigi Vanvitelli, Naples 80138, Campania, Italy
Author contributions: Pellegrino R and Gravina AG collected the literature, wrote the initial manuscript, conceptualised the table, conceptualised the structure of the text, critically revised the manuscript for important intellectual content, and read and approved the final version.
Conflict-of-interest statement: The authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Antonietta Gerarda Gravina, MD, PhD, Associate Professor, Division of Hepatogastroenterology, Department of Precision Medicine, University of Campania Luigi Vanvitelli, Via L. de Crecchio, Naples 80138, Campania, Italy. antoniettagerarda.gravina@unicampania.it
Received: March 18, 2025
Revised: April 2, 2025
Accepted: April 23, 2025
Published online: May 16, 2025
Processing time: 55 Days and 21.2 Hours
Core Tip

Core Tip: PuraStat® is a novel self-assembling peptide haemostatic agent used in digestive endoscopy. This commentary summarises the efficacy and safety profile of PuraStat® as discernible from the current literature, focusing on the study published in the World Journal of Gastrointestinal Endoscopy, highlighting its potential role and the need for further investigation.