Published online Mar 16, 2019. doi: 10.4253/wjge.v11.i3.231
Peer-review started: January 27, 2019
First decision: February 20, 2019
Revised: February 28, 2019
Accepted: March 11, 2019
Article in press: March 11, 2019
Published online: March 16, 2019
Biliary ductal cancer (BDC) is a lethal disease; however, the histological diagnosis of BDC is difficult.
Histological diagnosis of BDC is achieved by endoscopic biliary biopsy except for surgery. However, the appropriate method (i.e., the number of times, the number of ERCP sessions) for biliary biopsy is unknown.
This study aims to clarify the appropriate method of endoscopic biliary biopsy.
The subjects of this study were patients who were histologically diagnosed with BDC. The patients who could be diagnosed by biliary biopsy were determined as the positive group (P group), and the patients who could not be diagnosed by biliary biopsy were determined as the negative group (N group). The methods for ERCP procedures were compared between the P group and the N group.
Multiple ERCP sessions did not contribute to the improvement of the diagnosability of biliary biopsy.
If biliary cancer is not pathologically diagnosed after the first session of ERCP, other methods should be employed.
From the results of this study, several methods will be developed and tested for diagnosing BDC.