Hepatoprotective effect of silymarin

doi:10.4254/wjh.v6.i3.144

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 6, Issue 3

This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (16068)

All Articles published online

The chart showing PDF series, HTML series, Figures (1-1) series.

Item

Count

PDF

1360

HTML

12523

Figures (1-1)

150

Sum=14033

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

1134

Download

901

Sum=2035

Mar 27, 2014 (publication date) through Apr 25, 2024

Times Cited of This Article

Times Cited (255)

Journal Information of This Article

Publication Name

World Journal of Hepatology

ISSN

1948-5182

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Minireviews

World J Hepatol. Mar 27, 2014; 6(3): 144-149
Published online Mar 27, 2014. doi: 10.4254/wjh.v6.i3.144

Hepatoprotective effect of silymarin

Nancy Vargas-Mendoza, Eduardo Madrigal-Santillán, Ángel Morales-González, Jaime Esquivel-Soto, Cesar Esquivel-Chirino, Manuel García-Luna y González-Rubio, Juan A Gayosso-de-Lucio, José A Morales-González

Nancy Vargas-Mendoza, Juan A Gayosso-de-Lucio, Institute of Health Sciences, Autonomous University of Hidalgo State, Pachuca 42000, México

Eduardo Madrigal-Santillán, José A Morales-González, Laboratorio Medicina de Conservación, Escuela Superior de Medicina, Instituto Politécnico Nacional, México City 11340, México

Ángel Morales-González, Escuela Superior de Cómputo, Instituto Politécnico Nacional, Av. Juan de Dios Bátiz s/n esquina Miguel Othón de Mendizabal, Unidad Profesional Adolfo López Mateos, México City 07738, México

Jaime Esquivel-Soto, Cesar Esquivel-Chirino, Manuel García-Luna y González-Rubio, Faculty of Dentistry, UNAM, México City 07738, México

Author contributions: All of the authors participated equally in the creation of this document.

Supported by Proyecto SIP 20140856, ESM-IPN

Correspondence to: José A Morales-González, MD, PhD, Laboratorio Medicina de Conservación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón, Col. Casco de Santo Tomás, Del. Miguel Hidalgo, México City 11340, México. jmorales101@yahoo.com.mx

Telephone: +1-55-57296300-62753 Fax: +1-55-53963503

Received: November 3, 2013
Revised: January 27, 2014
Accepted: February 20, 2014
Published online: March 27, 2014

Core Tip

Core tip: One of the mechanisms of liver damage caused by alcohol is the generation of free radicals formed by the metabolism of this xenobiotic. Silymarin is an antioxidant that protects the liver from the free radical damage produced by alcohol metabolism. Silymarin is the most used natural compound for the treatment of hepatic diseases worldwide due to its antioxidant, anti-inflammatory, and anti-fibrotic activities. Silymarin functions by stabilizing biological membranes and increasing protein synthesis.