Relationship between nuclear morphometry, DNA content and resectability of pancreatic cancer

Table 1 Relationship between DNA contents, clinical charac-teristics and resectability

Variable Factor		Resectable group	Unresectable group	Correlation coefficient (r)
X1	Age (years)	46.5 ± 5.3	58.6 ± 0.7a	0.536b
X2	Tumor cells (n)			0.387
	Ductal	17(94%)	16(89%)
	Other	1(6%)	2(11%)
X3	Clinical stage (n)c			0.605b
	Stage I	9(50%)	0(0%)a
	Stage II	8(44%)	3(17%)
	Stage III	1(6%)	11(61%)a
	Stage IV	0(0%)	4(22%)
X4	Histological grade (n)			0.394
	Kloppel I	5(28%)	3(17%)
	Kloppel II	6(33%)	9(50%)
	Kloppel III	7(39%)	6(33%)
X5	Site (n)c			-0.545b
	Head of pancreas	16(89%)	10(56%)a
	Other	2(11%)	8(44%)a
X6	Size (cm3)	298.1 ± 101.5	634.7 ± 512.5a	0.575b
X7	Nuclear areas (µm2)	33.37 ± 8.42	34.74 ± 6.93	0.478
X8	Perimeter (µm)	24.90 ± 4.02	25.60 ± 3.02	0.367
X9	Minor axis (µm)	5.56 ± 0.68	5.67 ± 0.57	0.482
X10	Major axis (µm)	8.31 ± 1.10	8.56 ± 0.93	0.434
X11	Form factor	0.75 ± 0.05	0.70 ± 0.06	0.376
X12	IOD	1.64 ± 0.41	2.96 ± 0.55a	0.787b
X13	DNA ploidy (n)			0.735b
	Diploid/tetraploid	12(67%)	7(39%)a
	Aneuploid	6(33%)	11(61%)a

^aP < 0.05, vs resectable group,

^bP < 0.05, T test,

^cP < 0.05, resect-able group vs unresectable group