Effect of a single oral dose of rabeprazole on nocturnal acid breakthrough and nocturnal alkaline amplitude

Table 1 Effect of single dose of PPI on NAB

PPI group	n	Occurring cases (%)	Time range	pH (¯x ± s)	Persisting time (¯x ± s) (h)
RAB10 mg	15	9 (60%)	0:00-4:0	1.84 ± 0.55ac	4.10 ± 2.38
OME20 mg	15	9 (60%)	20:00-2:0	1.15 ± 0.31	5.40 ± 2.73
PAN40 mg	10	8 (80%)	20:00-6:0	1.10 ± 0.30	5.71 ± 2.60

^aP < 0.05 vs OME,

^cP < 0.05 vs PAN.

Table 2 Effect of single dose of PPI on NAKA

PPI group	n	Occurring cases (%)	Time range	pH ( ¯x ± s)	Persisting time (¯x ± s) (h)
RAB10 mg	15	9 (60%)	2.0-7.0	6.41 ± 0.45cb	4.65 ± 1.22acb
OME20 mg	15	8 (53.3%)	1.0-7.0	6.51 ± 0.82b	3.22 ± 1.89
PAN40 mg	10	5 (50%)	2.0-6.0	6.01 ± 0.92	3.15 ± 1.92
Control group	20	9 (45%)	1.0-6.0	5.30 ± 0.47	2.25 ± 1.23

^aP < 0.05 vs OME,

^cP < 0.05 vs PAN,

^bP < 0.05 vs healthy control group.