Studies on the relationship between the point mutation of ras oncogenes and the prognosis of patients with gastric cancer

Table 1 Correlation between ras point mutation and clinical and pathological parameters of gastric cancer

	n	Point mutationnegative	Point mutationpositive (%)
Histological types
Gland adenocarcinoma	20	18	2 (10.0)
Low differentiated carcinoma	29	22	7 (24.1)
Signet ring cell carcinoma	23	18	5 (21.7)
Mucinous carcinoma	16	14	2 (12.5)
Size
< 5 cm	47	41	6 (12.8)
> 5 cm	41	31	10 (24.4)
Serosal invasion
Without serosal invasion	40	38	2 (5.0)
With serosal invasion	48	34	14 (29.2)b
Lymph node metastases
Without lymph node metastases	35	33	2 (5.7)
With lymph node metastases	53	39	14 (29.2)a
Staging
Staging I and II	43	42	1 (2.3)
Staging III and IV	45	30	15 (33.3)c